PI3K, phosphatidylinositol-3-kinase, is a specific lipid kinase family. It is associated with cell proliferation and survival..Class-IA PI3K is heterodimers composed of catalytic subunit (p110) and regulatory subunit (p85). p85α is the most abundant regulatory subunit of PI3K family. PI3K-p85α partial cDNA was amplified by RT-PCR from Inner Mongolia Cashmere Goat (Capra hircus) and sequenced. The molecular characterization of the PI3K-p85α gene was described. The amplified fragment is 1152bp in length, corresponding to a polypeptide of 384 amino acids residues with 45.4 kDa predicted molecular mass. The cDNA nucleotide sequence has 98% identity with regulatory subunit alpha (PIK3R1) of bovine and 93% identity with human. The goat PI3K-p85α patial cDNA is cloned.
In this paper, the working mechanism and high characteristics of an InP/InGaAsP uni-traveling-carrier (UTC) double hetero-junction phototransistor (DHPT) has been analyzed. The UTC-DHPT employs a heavy doping base and two hetero-junctions to realize UTC structure to ease the contract between HPT responsivity and HPT working speed. Optical responsivity and optical transit frequency are analyzed physically through illustrated several kinds of paramistic capacitors in BE junction and BC junction under different electrical bias, optical bias and combined electrical and optical bias in this work. The results show that three-terminal (3T) working mode with combined electrical bias and optical bias in base achieves a highest maxim fT of 120GHz at collector current of 30mA and keeps the same optical responsivity (37.5A/W) compared with two-terminal (2T) working mode.
A second order differential filter with Q-enhancement and tunable active inductor is presented. The design technique for a tunable Q-enhancement SiGe HBT active inductor operating in the wide RF-band for the filter is described. Multi-regulated Cascode circuit is employed to enhance the quality factor Q by increasing the output impedance. Tunable active resistor is introduced to boost the tuning ability of the active inductor. Employing the proposed active inductor, the center frequency of the filter is tuned in the frequency of 1.05~2.45GHz by adjusting the bias current, Q reducing with different bias current can be compensated via tuning the feedback effective resistance of the active inductor, and Q has almost constant value of 209~225 at the frequency of 2.15GHz.
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