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BackgroundOsteoblasts-Osteoclasts has been a major area in bone disease research for a long time. However, there are few systematic studies in this field using bibliometric analysis. We aimed to perform a bibliometric analysis and visualization study to determine hotspots and trends of osteoblasts-osteoclasts in bone diseases, identify collaboration and influence among authors, countries, institutions, and journals, and assess the knowledge base to develop basic and clinical research in the future.MethodsWe collected articles and reviews for osteoblasts-osteoclasts in bone diseases from the Web of Science Core Collection. In addition, we utilized scientometrics software (CiteSpace5.8 and VOSviewer1.6.18) for visual analysis of countries/regions, institutions, authors, references, and keywords in the field.ResultsIn total, 16,832 authors from 579 institutions in 73 countries/regions have published 3,490 papers in 928 academic journals. The literature in this field is rapidly increasing, with Bone publishing the most articles, whereas Journal of Bone and Mineral Research had the most co-cited journals. These two journals mainly focused on molecular biology and the clinical medicine domain. The countries with the highest number of publications were the US and China, and the University of Arkansas for Medical Sciences was the most active institution. Regarding authors, Stavros C. Manolagas published the most articles, and Hiroshi Takayanagi had the most co-cited papers. Research in this field mainly includes molecular expression and regulatory mechanisms, differentiation, osteoprotection, inflammation, and tumors. The latest research hotspots are oxidative stress, mutation, osteocyte formation and absorption, bone metabolism, tumor therapy, and in-depth mechanisms.ConclusionWe identified the research hotspots and development process of osteoblasts-osteoclasts in bone disease using bibliometric and visual methods. Osteoblasts-osteoclasts have attracted increasing attention in bone disease. This study will provide a valuable reference for researchers concerned with osteoblasts-osteoclasts in bone diseases.

Although transition metal silicates are recognized as high potential and attractive materials for next-generation lithium-ion batteries (LIBs) due to their efficient energy storage, earth-abundance without pollution, low cost, and easy preparation, however, the unstable electrochemical stability originating from the intrinsic mechanism involved in long-term cycling tests is always of concern and needs to be decoupled stepwise. Herein, a strategy is proposed to overcome the challenges through the construction of a heterostructure using a facile hydrothermal method in combination with carbon nanotubes (CNTs), the composite. By tailoring a capacitive contribution over diffusion toward total charge storage in the heterostructure, CNT-coated heterostructural copper− nickel silicates (CNT@NiCuSi) were employed as the anode to achieve a relatively high capacity (412 mAh g −1 at 0.2 A g −1 ) and prolonged life for durable LIBs (91% retention after 1000 cycles at 0.5 A g −1 ). The heterostructure generated by NiSi/CuSi could lower the polarization of the composite and elevate its cycle stability, rendering the metal silicate favorable for LIBs. As a consequence, the practical application is evaluated by assembling a full cell based on CNT@NiCuSi as the anode and LiNi 0.8 Co 0.1 Mn 0.1 O 2 (NCM811) as the cathode yielding a reversible capacity of 429 mAh g −1 , along with a decent capacity retention of 221 mAh g −1 at a current density of 0.5 A g −1 after 300 cycles. This strategy opens an avenue for constructing long-life metal silicate-based nanocomposites for LIBs.

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