Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is an important clinical event characterized by an aggravation of the patient's respiratory symptoms whose degree exceeds the range of daily variation, leading to changes in the drug treatment regimen; it is the main cause of death from chronic obstructive pulmonary disease (COPD) on a global scale (Shen & Wang, 2020). The Global Burden of Disease study pointed
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