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Endosonics is an ultrasonic synergistic system of root canal instrumentation and disinfection. Specially made endosonic dies and diamond instruments are energized by means of a Cavitron ultrasound generator (above 20 kHz frequency). An endosonic insert is designed to allow the traditional endodontic irrigant, sodium hypochlorite, to pass through and along the endo‐sonic files. The irrigant is activated by the ultrasonic energy imparted from the energized instruments and the root canal becomes an ultrasonic bath. Thus, endosonics is a synergistic system. The ultrasonic energy makes the files vibrate and oscillate, facilitating the instrumentation of the root canal and, in addition, activates the irrigant for canal disinfection.