No abstract

A major breakthrough in sid came up when analysis of power co cryptographic device led to discovery of th analysis technique popularly known as Powe now one of the most volatile and successful s This technique uses the power consumed b system as the main parameter to identify algorithms as well as the secret key used. T the system are statistically analyzed and the these traces and the cryptographic techni break the security. This attack has been succ on various cryptographic algorithms like D ECC which are implemented on cryptogr smart cards, FPGA, DSP, ASIC etc. In this review on the power analysis attack and its brief detail on some of the power analysis att and FPGA have been presented. Couple of m such attacks has also been mentioned Keywords-cryptosystem, power analysis, smart cardsI.

No abstract

A fragment-based drug discovery (FBDD) approach has traditionally been of utmost significance in drug design studies. It allows the exploration of large chemical space to find novel scaffolds and chemotypes which can be improved into selective inhibitors with good affinity. In the current work, several public domain chemical libraries (ChEMBL, DrugCentral, PDB ligands, COCONUT, and SAVI) comprising bioactive and virtual molecules were retrieved to develop a fragment library. A systematic fragmentation method that breaks a given molecule into rings, linkers, and substituents was used to cleave the molecules and the fragments were analyzed. Further, only the ring framework was taken into the consideration to develop a fragment library that consists of a total number of 107,614 unique fragments. This set represents a rich diverse structure framework that covers a wide variety of yet-to-be-explored fragments for a wide range of small molecule-based applications. This fragment library is an integral part of the molecular property diagnostic suite (MPDS) suite that can be used with other modeling and informatics methods for FBDD approaches. The fragment library module of MPDS can be accessed at http://mpds.neist.res.in:8085 . Graphical abstract Supplementary Information The online version contains supplementary material available at 10.1007/s11030-022-10506-5.