Work and Family Stress is Associated with Menstrual Disorders but not with FibrocysticChanges: Cross-sectional Findings in Chinese Working Women: Mei ZHOU, et al. School of Public Health, Kunming Medical University, ChinaObjectives: To explore the separate and combined effects of work and family stress on menstrual disorders and fibrocystic changes in Chinese working women. Methods: Data were obtained from a cross-sectional study of 1,642 female railway workers. The EffortReward Imbalance Questionnaire and Family Stress Scale were used to measure work stress and family stress, respectively; the menstrual and breast conditions were evaluated by gynecologic interview and a medical examination. Multivariate log-binomial regression was performed to analyze the associations. Results: Menstrual disorders were found in 59.3% of female workers, and 54.8% had fibrocystic changes. The risk of menstrual disorders was significantly elevated with respect to work and family stress. The highest risk was found in the group with combined exposure to both work and family stress (RR with 95% CI 1.33 (1.18-1.49)). No significant association between stress and fibrocystic changes was observed. Conclusions: Menstrual disorders were associated with stress from work and family life, but not fibrocystic changes, in working women. Tailored intervention measures reducing the burden of stressful psychosocial work and family environment are needed to improve women's reproductive well-being. (J Occup Health 2010; 52: 361-366)