Pressure sensor has become an important part of physiological condition monitoring system because it can respond to small pressure in human activities. Tissue paper has been studied as a carrier of sensitive unit layer for pressure sensors in recent years due to its internal pore structure and wrinkle morphology of surface. In this work, the pore structure of the tissue paper is improved by the principle of hydration and destruction of hydrogen bonds. Based on flexible substrate of NaOH modified tissue paper (NMTP) with enhanced pore structure, combined with dip-coating composite conductive filler, the pressure sensor is fabricated by sandwiching the sensitive unit between the interdigital electrode and the microdome elastomer through layer-by-layer assembly method. Thanks to the excellent interfacial resistance effect of porous NMTP under pressure, the sensitivity of NMTP-based pressure sensor is as high as 37.5 kPa −1 in a pressure range of 0-2 kPa. Finally, the follow-up studies on pressure sensors have been proven to be applicable to a variety of physiological activity such as pulse detection, respiration detection and voice recognition. The NMTP-based sensitive unit provides alternative strategy to improve performance of pressure sensors and extends potential applications in monitoring human physiological activities.

Disk model is usually used to represent graphene nanoplatelets (GNPs) which are considered as frame‐like structure with edges and corners, and it has lack of quantitative accuracy. In order to minimize error caused by morphology, distribution, and interaction between GNPs and matrix, square and folded plate models were constructed to predict the percolation volume fraction (ϕc) of GNPs‐based nanocomposites by calculating connection possibility. Meanwhile, disk model is used for comparison. The results revealed that the ϕc of square and folded plate models is smaller than that of disk model with consistent parameters, and it is concluded that the ϕc of GNPs‐based nanocomposites predicted by disk model should be higher than that of experimental. The correctness of mixed model of square and folded plate is also verified by experimental. Due to the agglomeration of GNPs under the actual situation, the result of simulation is slightly smaller than that of experiment.