Our experience suggests that BSL-3 laboratory operating principles should be among the special requirements for performing autopsies of contaminated bodies and that they can safeguard the clinicians and the environment involved in these procedures.

APSP shows an apparent efficacy in treating PCH and is worthy of application in clinical practice.

To investigate the characteristics of blood lipid metabolism in twin pregnancy combined with gestational diabetes mellitus (GDM) or pregnancy-induced hypertension (PIH). This study retrospectively analyzed 96 cases of twin pregnancy and 232 cases of full-term singleton pregnancy. General data and blood lipid levels, including triglyceride (TG) and total cholesterol (TC), between twin and singleton pregnancies were compared. Blood lipid levels between GDM (PIH) and non-GDM (non-PIH) groups in twin pregnancy were compared. The TG level for twin pregnancy was higher than that for singleton pregnancy (p<0.05), while there was no significant difference in the TC level between them (p>0.05). The TG level in the GDM group was higher than that in the non-GDM group (p<0.05), while the TC level in the GDM group was not different from that in the non-GDM group (p>0.05). The TG level in the PIH group was higher than that in the non-PIH group (p<0.05), while there was no difference in the TC level between them (p>0.05). Logistic regression analysis showed that age was a risk factor for GDM and PIH in singleton and twin pregnancies. The lipid levels in twin pregnancy increased with the increase of gestational age, and the TG level in twin pregnancy complicated with GDM or PIH was higher than that in twin pregnancy without GDM or PIH, indicating that the blood lipid metabolism was related to the occurrence of GDM and PIH in twin pregnancy to some extent.

Objective To investigate clinical values of early-pregnancy (8–13 weeks) glycated hemoglobin (HbA1c), fasting plasma glucose (FPG), and body mass index (BMI) in screening gestational diabetes mellitus (GDM). Methods A total of 1120 cases underwent a 75 g oral glucose tolerance test (OGTT), of which 216 cases with GDM were selected as the study group, and 278 cases without GDM were selected as the control group. FPG, HbA1c, and BMI in early pregnancy were measured. The correlation between FPG, HbA1c and BMI in early pregnancy and the incidence of GDM was analyzed by binary logistic regression, and the value of each index in predicting GDM alone or in combination was evaluated. Results FPG, HbA1c, and BMI in early pregnancy in the GDM group were higher than those in the control group, and the differences were statistically significant (P &lt; .05). Binary logistic regression analysis showed that FPG, HbA1c, and BMI were risk factors for GDM in early pregnancy (odds ratio [OR] values were 3.374 [P &lt; .05], 4.644 [P &lt; .001], and 1.077 [P &lt; .001], respectively). The area under the receiver operating characteristic (ROC) curve of FPG, glycated hemoglobin, and BMI in screening GDM for early pregnancy were 0.647, 0.661, and 0.608, respectively, while the area under the ROC curve of the combination of these 3 indicators was 0.736. Conclusion We found that FPG, HbA1c, and BMI in early pregnancy might be the potential risk factors for the occurrence of GDM, and the combination of them had certain clinical predictive value for GDM. However, it is still necessary for more studies, especially prospective studies, to validate our findings in the future.

Fan et al.: Combined Effects of Ulinastatin and Dexmedetomidine on OLV PatientsTo evaluate the protective effects of ulinastatin combined with dexmedetomidine on patients undergoing one lung ventilation. A total of 100 patients who underwent thoracoscopic partial lobectomy in our hospital were selected and randomly divided into control group (Group N), ulinastatin pretreatment group (Group U), dexmedetomidine continuous pumping group (Group D) and combined treatment group (Group U+D) (n=25). Their intraoperative data and objective indices reflecting the lung function at T1, T2 and T3 were compared. The expression levels of inflammatory factors were compared at T0, T1, T2, T3 and T4. Lung dynamic compliance and oxygenation index rose first and then declined, while respiratory index declined first and then rose in all patients from T1 to T3. At T3, lung dynamic compliance and oxygenation index were significantly higher, while respiratory index was significantly lower in Group U+D than those in the other groups (p<0.05). lung dynamic compliance, oxygenation index and respiratory index had significant differences in Group U and D compared with those in Group N, but they had no significant differences between Group U and D (p>0.05). The levels of inflammatory factors rose first and then declined in all patients from T0 to T4. At T3 and T4, the levels of pro-inflammatory factors were significantly lower, while the level of anti-inflammatory factor was significantly higher in Group U+D than those in the other groups (p<0.05). The levels of inflammatory factors had significant differences in Group U and D compared with those in Group N (p<0.05), but they had no statistically significant differences between Group U and D (p>0.05). Group U+D had a significantly lower incidence rate of postoperative pulmonary complications and a significantly shorter length of stay after surgery than those of Group U, D and N (p<0.05). Dexmedetomidine and ulinastatin can alleviate the damage caused by one lung ventilation to the lung to a certain extent and the combination of them has the optimum effect.