There is a lot of study in adults investigating the Triglyceride-Glucose (Ty-G) index. However, a limited study has been searched in the pediatric age group. Moreover, to the best of our knowledge, there is no study on Turkish children. The aim of this study, to investigate the usability of the triglyceride-glucose index as an indicator of insulin resistance in obese adolescents and to calculate the cut-off values.Method: Six hundred twenty-three pubertal obese adolescents (266 boys, and 357 girls) were retrospectively evaluated. Ty-G index and HOMA-IR levels were calculated. ROC analysis was used for the estimations of the Ty-G index cutoff value.Results: There was positive correlation between HOMA-IR and Ty-G index in boys (r=0.255, p<0.001), in girls (r=0.402, p<0.001), and all study groups (r=0.323, p<0.001). Ty-G index cutoff value for insülin resistance in pubertal obese adolescents was calculated as 8.42 with 70.1 % sensitivity and 59.3 % specificity for all study groups; 8,38 with 71.1 % sensitivity, and 48.3 % specificity for boys; 8,27 with 80% sensitivity, and 52.9% specificity for girls.Conclusions: Ty-G index may be a reliable indicator for insülin resistance in pubertal obese adolescents. More attention should be given fort his marker with prospective studies.

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