In this study, Broussonetia kazinoki stem extract (BKSE) had potent antioxidant activity and inhibited collagenase, which breaks down collagen in skin, activity. These results suggest that BKSE has the potential to exhibit antioxidant activity and suppress collagenase activity in skin. Collagen is the main structural protein in the extracellular space in skin connective tissue. BKSE can help maintain skin's collagen content by eliminating reactive oxygen species and inhibiting collagenase activity. Through these activities, BKSE can be used as a cosmetic raw material to suppress skin wrinkles.
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