Abstract. An Er:YAG laser with 2940-nm wavelength and 250-μs pulse duration is used to generate a microjet that is ejected at ∼50 m∕s in air. The strength of the microjet depends on the bubble dynamics from the beamwater interaction within the driving chamber as well as the discharging of the drug solution underneath the elastic membrane that separates the drug from the driving liquid. The jet characteristics, such as velocity, volume, and level of atomization, are obtained by high-speed camera images taken at 42,000 fps. The enhancements in jet volume (dosage) and repeated jet generation, which are aimed at making the injector suitable for general clinical applications, are achieved. The generation of repeated microjets is achieved with the help of a stepping motor that provides a uniform pressure within the drug reservoir before an ejection occurs through a micro nozzle. Also, two types of human growth hormones are used for monitoring any potential thermal damage to the drug solution due to a repeated laser ablation when driving the microjet. We provide strong evidence to support that the drugs, as they are injected to porcine skins, are free of the damage associated with the present delivery method. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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[1] In a new Tatiana-2 mission the measurement of transient luminous events (TLE) in the Earth atmosphere in nadir direction are planned. Near UV temporal images of TLE in millisecond scale will be measured together with temporal profiles in 8 channels of wide spectrum of TLE emission. Simultaneously temporal variation of electron flux at the satellite orbit will be measured. Aims of these measurements are to continue research of bright UV flashes, started in the Tatiana-1 mission (Universitetsky-Tatiana satellite), their global distribution, their rate over oceans and continents, and their possible correlation with lunar phase. Special attention will be paid to search for correlation between UV flashes from the atmosphere and variations of electron flux in the atmospheremagnetosphere system.

A pyrotechnic device that consists of a donor/acceptor pair separated by a gap or a bulkhead relies on the shock attenuation characteristics of the gap material and the shock sensitivity of the donor and acceptor explosives. In this study, a miniaturized exploding foil initiator, based on high pulsed electrical power generator, was designed to launch a micro Kapton® flyer for impact initiation of a high explosive in order to understand its performance characteristics. Here, the explosive substance was replaced with a witness plate because the flyer poses various flight motions of rotation, bend, and fragmentation due to its extreme thinness. By using a Velocity Interferometer System for Any Reflector and ANSYS Explicit Dynamics, the averaged velocity of a flyer is measured, which then allows for the calculation of the shock pressure and the duration imparted to the explosive for an initiation. Subsequently, the relationship between the flyer velocity, the amplitude, and the width of impact loading can be used to assess the performance of the designed exploding foil initiator of a micro pyro-mechanical device.

To meet the rising demand for miniaturizing the pyrotechnic device that consists of donor/acceptor pair separated by a bulkhead or a thin gap, the shock initiation sensitivity in the microscale gap test configuration is investigated. For understanding the shock attenuation within a gap sample (304 stainless steel) thickness of 10∼800 μm, the laser-generated shock wave in water confinement is adopted. The shock properties are obtained from the free surface velocity by making use of a velocity interferometer system for any reflector (VISAR). Analytical models for plasma generation in a confined geometry and for evolution and decay of shock waves during the propagation are considered. The shape and amplitude of the laser-driven initial pressure load and its attenuation pattern in the gap are effectively controlled for targeting the microscale propagation distance and subsequent triggering pressure for the acceptor charge. The reported results are important in the precise controlling of the shock strength during the laser initiation of microscale pyrotechnic devices.