No abstract

Quantitative and structural functional analysis of granulation tissue cells during treatment with protein-polysaccharide dressing Collahit F was carried out. The preparation effectively cleansed the wound from detritus, prevented secondary infection due to stimulation of the functional activity of macrophages and due to the effect of its antiseptic component (furagin), and stimulated proliferative activity of fibroblasts and granulation tissue microvessels on day 5 of treatment, thus promoting repair processes in the wound.

No abstract

Laboratory studies of collagen-based compositions demonstrated digispon to be the most effective agent for clinical use. Digispon is permeable to vapor and air, plastic, ensures prolonged dosed release of dioxydine into the wound, stimulates the growth of granulation tissue, accelerates marginal and islet epithelialization, and reduces the likelihood of the formation of coarse scar tissue. Radioautographic study of wound granulation tissue in experimental animals with modeled nonsuppurative inflammation showed that the principal processes ensuring wound healing during the application of collagen-based agents occur in the early stages, with an increase in the number of fibroblasts, including the proliferating variety, and blood vessels.