S23viruses were seen in 33.3% and 43.9% of WUV and KIV samples respectively. The median age range for WUV was 0−2yrs and KIV was 2−4yrs.
Conclusions:This study suggests that WUV is a more likely pathogen in immunocompetent children between 0−2yrs, whereas KIV is prevalent in the immunosuppressed population, mainly children between 2−4yrs, as a coinfection with other respiratory viruses. There are a paucity of data regarding the exact clinical role of these polyomaviruses as human pathogens thus requiring prospective longitudinal and seroprevalence studies.
Background: Knowledge of pulmonary complications (PCs) in children after hematopoetic stem cell transplantation (allo-HSCT) is limited; most data are from adult studies.
Case:We describe a 8 year old girl with high risk acute myeloid leukemia who developed graft versus host disease (GVHD) on Day 20, Cytomegalovirus (CMV) pneumonia on Day 50 and Cryptogenic organizing pneumonia (COP) on Day 170 after allo-HSCT.
Discussion:Cryptogenic organizing pneumonia is a rare noninfectious PCs that can be idiopathic or have several risk factors as a secondary causes, such as viral respiratory infections, drugs, GVHD and allo-HSCT. Viral respiratory infections and alloimmune lung syndromes have been reported in a few patients who have undergone transplantation.
Conclusion:Transplant physicians should be kept in mind for the development of alloimmune lung syndrome in the form of COP following CMV pneumonia in patients after allo-HSCT.
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