A 15-year-old child followed for Best vitelliform macular dystrophy presented to the clinic with an abrupt visual impairment of his left eye. Fundus examination showed bilateral vitelliform lesions, with serous retinal detachment and adjacent retinal hemorrhage in the left eye. Fluorescein angiography and optical coherence tomography confirmed the diagnosis of type-2 choroidal neovascularization complicating the Best disease. The juxtafoveal location of the choroidal neovascularization prompted us to realize monthly intra-vitreous injections of bevacizumab. After the fourth injection, we observed visual and anatomical improvement that remained stable after a 12-month follow-up. It’s important to look for complications in front of a sudden decrease in visual acuity in Best disease.

Sarcoidosis, or Besnier-Boeck-Schaumann disease, is systemic granulomatosis of an unknown etiology characterized by the formation of immune granulomas in the affected organs. The clinical presentation can be very variable [1]. The diagnosis is made on a bundle of clinical, paraclinical and anatomopathological arguments when a biopsy is performed. The most commonly affected organs are the mediastinal lymphatic system, lungs, skin, and eyes. Ocular manifestations of sarcoidosis could take very different forms. We could find it in one in four patients and it may be revealing of sarcoidosis in 19% of cases [1]. All the tunics of the eyeball and the ocular adnexa can be involved.

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