Summary. Material and methods. On an experimental material at modelling of acute and chronic nephritic insufficiency at 75 white not purebred rats action research a crioextract ofplacenta (CEP) on morphology and functional indicators of kidneys is carried out. Results and discussion. Introduction CEP in early terms of damage of kidneys leads to fast elimination of changes of an epithelium of the tubular device and prevents development a CKI. The effect from introduction CEP remains about 16 weeks. Conclusions. Under the influence ofCEP in the beginning of development of acute kidney insufficiency function of kidneys remains. At the generated chronic insufficiency function of kidneys improves for short term and introduction ofCEP does not influence on development CKI.

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