The high incidence of the event and the lack of understanding of the nature of the toxin and its pathophysiological mechanism require continued monitoring of poison cases, botanical and biochemical analysis, and experimental studies.

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The aim of this experimental study was to measure the rupture stress point of a fibrin clot situated on a liver, in realistic surgical conditions. The experimental method was carried out with a machined wooden cylinder bonded on the liver, connected with a wire to a setup and pulled at a constant speed, and a sensor was placed on the wire measuring the applied strength. This method, realized in the dog, made it possible to validate a precise and reproducible method designed for testing the adhesive characteristics of biological sealant-collagen bonding on the liver.

In a group of 22 patients with idiopathic fecal incontinence treated by postanal repair (PAR), functional results were determined with a postoperative interval of 3 and 34 ± 9 months. Incontinence was reduced in 10 patients, and 12 regained normal continence. In all patients, continent or not, pre- and postoperative studies (3 months after PAR) showed no modification of maximum resting pressure and of anal canal length while in continent patients, maximal voluntary contraction values were higher without being significant. Comparison of preoperative and 3-month postoperative defecographic X-rays showed no modification of either anorectal angle values, or of perineal descent. Isolated repair of striated sphincteric muscles, without internal sphincter repair, could result in the absence of resting pressure variation, and explain the lack of incontinence correction in 10 of our patients.