Intrauterine administration of a phytopreparation from horseradish root for 5-6 consecutive days once a day for 100 ml contributed to the treatment of catarrhal-purulent endometritis in cows, the restoration of the uterine mucosa occurred gradually and was completed by the time of 36-40 days from the start of the course of treatment. The introduction of a phytopreparation immediately after the separation of the afterbirth or the provision of obstetric care for 100 ml for 2-3 days in a row, allowed to prevent the development of catarrhal-purulent endometritis.

The article presents the results of studies on the etiopathogenesis, clinical signs of postpartum catarrhal-purulent endometritis in cows, pathomorphological and histostructural changes in the geni-tals at the beginning of the disease and the results of treatment with intrauterine use of non-antibiotic, foaming and iodine-containing liquid drug "Metrasil". We believe that the restoration of the body mucosa and uterine horns as a result of treatment is difficult and long-lasting and ends by 30-35 days after the start of therapy and ends simultane-ously with positive processes and in the macroscopic picture of the organ.