Capital structure is an important thing to consider by companies in order to avoid financial difficulties and the potential of bankruptcy. This study aims to determine the effect of profitability, asset structure, and company growth towards capital structure. This research was conducted on property and real estate companies listed in Indonesia Stock Exchange during 2014 - 2018. The number of samples used in this study are 27 companies with an observation period of 5 years. The analysis technique used is multiple linear regression analysis. The results showed that profitability has no significant effect on capital structure, but asset structure and company growth have positive and significant effect on capital structure. Keywords: capital structure, profitability, asset structure, company growth.