The anatomical abnormalities of the nose and paranasal sinuses are the most common causes of rhinosinusitis. These anatomical variations can cause obstruction of the ostiomeatal complex (OMC) and interfere with the mucociliary clearance which allows the occurrence of chronic rhinosinusitis. Knowing the anatomic variations of the nose and paranasal sinuses in rhinosinusitis patients whose undergo operative procedure at Sanglah Provincial General Hospital is important because it can be used as a reference for proper intervention to treat rhinosinusitis. This research is a descriptive study in the Ear Nose Throat - Head Neck Departement, Udayana University Medical School / Sanglah Provincial General Hospital Denpasar, from January 2018 to December 2018. The research location is at the ENT clinic, Sanglah Hospital, Denpasar. This research will be conducted in approximately 2 months (January 2019 to February 2019). The sample from this study was all rhinosinusitis patients who underwent operative procedure, both male and female for the period of 1 January – 31 December 2018. Based on the results of the research data, it was found that the most anatomic variation was septal deviation which was 24 people Anatomic variations cause chronic sinusitis by causing obstruction in the ostiomeatal complex (OMC) and affecting the mucociliary transport pattern. The most anatomical variation in this study is septal deviation.

Background: Anthropometry is the measurement of human and more inclined to focus on the dimensions of the human body. Nasal indexes can be used to help determine personal identity, especially race, ethnic and gender differences. Purpose: The general objective of this study was to find out the results of nasal index anthropometric studies on Bali Aga populations in Tenganan. Methods: In this study, 20 samples (4 male and 16 female) within age group of 17-30 years old of Bali Aga population in Tenganan Village were measured strictly on Frankfort’s plane with the help of a sliding caliper. Results: The results of nasal anthropometry measurements obtained an average width of the nose of 38.790 mm, the average nose length of 45.490 mm and nasal index measurements obtained an average of 85.6416. Conclusion: Nasal index can be used to help determine personal identity, especially race, ethnic and gender differences. The result of nasal index in Bali Aga population in Tenganan Village is the Platyrrhine nose (wide nose). Latar belakang: Antropometri adalah pengukuran manusia dan lebih cenderung terfokus pada dimensi tubuh manusia. Nasal indeks dapat digunakan untuk membantu menentukan identitas personal, terutama perbedaan ras, etnis, dan jenis kelamin. Tujuan: Tujuan umum penelitian ini adalah untuk mengetahui hasil studi antropometri nasal index pada populasi Bali Aga di Tenganan. Metode: Studi ini melibatkan, 20 sampel (4 laki-laki dan 16 perempuan) dari penduduk Bali Aga Desa Tenganan yang diukur pada Frankfort’s plane dengan bantuan jangka sorong. Hasil: Pada hasil pengukuran antropometri hidung didapatkan rata-rata lebar hidung sebesar 38.790, rata-rata panjang hidung sebesar 45.490 serta pengukuran nasal index didapatkan rata-rata 85.6416. Kesimpulan: Nasal indeks dapat digunakan untuk membantu menentukan identitas personal, terutama perbedaan ras, etnis, dan jenis kelamin. Hasil nasal index pada populasi bali aga di Desa Tenganan adalah jenis hidung Platyrrhine (hidung lebar).

The safety and immunogenicity of the two-dose injections of the CoronaVac vaccine (Sinovac Life Sciences) have been reported in Phase 1 and 2 trials. 1,2 After the approval of CoronaVac by the Indonesian government, the coronavirus disease 2019 (COVID-19) vaccination program was launched in January 2021, with the first administration batch targeted towards healthcare workers. However, published data regarding the humoral immune response after Cor-onaVac vaccination in subjects not included in clinical trials are scarce. Therefore, this report aims to evaluate the effectiveness of two doses of CoronaVac vaccine by investigating the level of total Ig anti-receptor binding domain (RBD) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This is a retrospective study carried out using nonprobability sampling. Subjects were included based on the fulfillment of the following criteria: (1) healthy volunteers; (2) healthcare workers receiving Cor-onaVac vaccine between January and March 2021; (3) has received two doses of CoronaVac (at a 2-week interval [0 and 14 days], with each dose containing inactivated SARS-CoV-2 virus 3 mcg [600 SU] in 0.5 ml); (4) has had a measurement of the Ig anti-RBD quantified by Elecsys Anti-SARS-CoV-2 S (Roche, cut-off value ≥ 0.8 U/ml) after the second dose of CoronaVac vaccine. The Elecsys Anti-SARS-CoV-2 S serology assay is a quantitative electrochemiluminescence immunoassay (ECLIA) utilizing a recombinant protein representing the RBD of the spike antigen and captures predominantly anti-SARS-CoV-2 IgG. 3,4 This study was approved by the Faculty of Medicine and Health Science, Maulana Malik Ibrahim State Islamic University of Malang ethics committee (Ref. No. 023/EC/KEPK-FKIK/2021), and informed consent was obtained from all subjects.The Ig anti-RBD measurement time was varied, ranging from 7 to 49 days after the second dose of the CoronaVac vaccine. Subjects were hence grouped according to the time of Ig anti-RBD measurement. The Ig anti-RBD level between groups was statistically analyzed either by one-way analysis of variance (ANOVA) or paired/ unpaired t-test using SPSS version 25 with a significance threshold of p < 0.05, and all figures were generated using the Graphpad PRISM.Initially, a total of 131 subjects, consisting of 59 male (45%) and 72 female (55%) healthcare workers (mean age overall, 35.

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ABSTRAK Latar Belakang: Serumen yang menumpuk merupakan alasan utama saluran telinga bisa tersumbat. Permasalahan THT pada siswa usia sekolah dasar harus mendapat perhatian yang serius karena akan mempengaruhi proses pendidikan di sekolah. Penelitian ini bertujuan untuk mengetahui jumlah kasus serumen obsturan yang terdapat pada siswa usia sekolah dasar di Tabanan, Bali.Metode: Penelitian menggunakan rancangan penelitian deskriptif cross sectional. Penelitian dilakukan di 12 sekolah dasar di Kabupaten Tabanan, Bali. Penelitian dilakukan mulai bulan Januari-Desember 2019. Subjek penelitian diambil dari siswa sekolah dasar dari kelas 1 sampai kelas 6. Pengambilan sampel dilakukan dengan cara total sampling.Hasil: Jumlah sampel siswa laki-laki 760 sampel (55.6%) dan siswa perempuan 606 sampel (44.4%). Usia yang terbanyak adalah 12 tahun (19.6%) sedangkan yang paling sedikit adalah 6 tahun (2.1%). Permasalahan serumen obsturan terdapat pada 499 sampel (36.5%). Letak serumen yang terbanyak adalah bilateral (55.5%).Kesimpulan: Serumen obsturan merupakan permasalahan yang cukup tinggi pada siswa usia sekolah dan dapat mengganggu proses kegiatan belajar mengajar.