Relevance. Noise is the most common harmful factor in the production of titanium alloys. The aim of the study is to identify age and gender features of the formation of general somatic morbidity associated with the impact of industrial noise at a large metallurgical enterprise. Scope and methods. The study compared the prevalence of chronic pathology of 4681 people who have contact with noise above 80 dBA, and those who are not exposed to noise using the methodology of occupational risk analysis of the Research Institute of Occupational Medicine. academician N. F. Izmerov according to the results of a periodic medical examination The results. The formation of general somatic pathology of many systems of the body under the influence of industrial noise occurs from the first years of operation. An increased risk of developing ear pathology was identified with work experience of more than 7 years. Men under the influence of noise had a significantly higher prevalence of diseases of the ear and digestive organs than women, with higher risks compared to those who were not exposed to noise and a medium to high relationship with working conditions. Conclusion. The revealed features of the formation of general somatic pathology under the influence of industrial noise allow us to recommend the introduction of health and rehabilitation programs from the first years of working in noise, even during the period of adaptation of young workers to the production environment.

Relevance. Local vibration is a significant factor in the production environment of metallurgical production, which affects health and efficiency. The aim of the study is to identify the exposure, gender and age features of the formation of general somatic morbidity associated with the impact of local vibration in the production of titanium alloys. Scope and methods. The prevalence of general somatic pathology was compared in 2596 workers who have contact with local vibration, with varying degrees of harmfulness of working conditions, and non-exposed persons according to the results of periodic medical examination using the methodology of occupational risk analysis of the Research Institute of Occupational Medicine. academician N. F. Izmerov. Results. At comparison of prevalence of a somatic pathology at workers in contact to local vibration to not exhibited persons according to medical inspection, and at different degree of harm of working conditions, are revealed the raised risks of formation of diseases nervous, kostno-muscular, endocrine systems, respiratory organs, digestion, an ear, a skin, an arterial hypertensia, the mental frustration, the raised weight of a body, gynecologic diseases with a tendency of growth of the majority of them at the big levels of vibration, more often at small, less often - average degree of communication with working conditions. The frequency of pathology in exposed workers was higher in all age groups. Average degree of communication with working conditions of a gynecologic pathology at the age of 18-25 years was marked. At men frequency of a pathology of respiratory organs, digestion is revealed authentically big, than at women; an ear; skin at the big relative risks 1,2-1,3, of the raised arterial pressure and hyperglycemia. Conclusion. A higher frequency of visceral pathology of a number of body systems under the influence of local vibration of high levels may justify the need to develop differentiated preventive programs to minimize its negative impact, taking into account the identified features in sex and age groups.

Introduction. Most studies on the morbidity of workers with fluorine compounds are devoted to occupational medicine at aluminium industry enterprises. The aim of the study is to identify the exposure, gender and evolutionary features of the formation of general somatic morbidity associated with chronic occupational exposure to hydrofluoride in the production of titanium alloys. Materials and methods. The analysis of the prevalence of chronic pathology according to the medical examination of 562 workers in contact with hydrofluoride and the incidence of temporary disability according to 29949 disability sheets in comparison with non-exposed persons of the same enterprise is given. Results. With an increase in the degree of harmfulness of working conditions, there was an augmentation increase in the risk of developing pathology of the respiratory organs, eyes, musculoskeletal system, arterial hypertension and hypercholesterolemia. In the working conditions of Class 3.1, an increased prevalence of diseases of the nervous and genitourinary systems with a moderate degree of occupational conditionality was revealed (relative risks (RR) 1.6 and 2.0, respectively, р < 0.05), class 3.2 - a high degree of professional conditionality of respiratory diseases (RR = 2.8). When working in harmful working conditions, there was an average degree of occupational conditionality of nervous system diseases in women (RR = 1.9) and a small degree of arterial hypertension in men (RR = 1.2). The prevalence of general somatic pathology in all age groups was higher than in non-exposed persons of the same age. Conclusion. Hydrofluoride in the production of titanium alloys was proved to be a trigger contributing to the formation of the pathology of the respiratory, circulatory, digestive, ear, eyes, skin, blood, musculoskeletal, nervous, endocrine, and genitourinary systems.