Purpose: to assess the effectiveness of carbon dioxide laser light in the treatment of benign skin neoplasms.Material and methods. The researchers have analyzed outcomes in 1394 patients treated for benign skin neoplasms. In the main group (n = 1184), laser photocoagulation (vaporization) and laser photohydraulic preparation were applied. Laser surgical devices “Lancet-1” and “Lancet-2” in continuous and pulsed modes, power up to 20 W, focused beam up to 1 mm were used. In the control group (n = 210), traditional techniques (excision and electrocoagulation) were applied.Results. High effi ciency of CO2 laser light for the removal of benign skin neoplasms has been confi rmed. Such a technique has a minimal rate of complications and relapses and satisfactory aesthetic outcomes, compared to the conventional treatment.Conclusion. Carbon dioxide laser light is highly effective for treating benign skin neoplasms.