Summary. Disruption of the motor-evacuation function of the digestive canal is an integral cause of the adverse course of acute obstruction of the small intestine and as a consequence of high lethality in this pathology. Purpose of the study. To study the motor activity of the gastrointestinal tract in patients with acute obstruction of the small intestine and its effect on the course of the disease in the postoperative period to create effective, sound methods of treatment of these patients. Materials and methods. Complexly after surgery, 221 patients with acute obstruction of the small intestine were examined. Used clinical and instrumental methods for the study of motor-evacuation function of the gastrointestinal tract (electrogastrography, electroenterography, phonoenterography), determined the degree of intoxication syndrome (leukocyte index of intoxication, molecules of medium mass), nonspecific resistance to organism operating-anesthetic index on ASA scale. Results and its discussion. Functional state of the patient with acute obstruction of the small intestine, its comorbidity affects the degree of operativeanesthesiological risk and the state of the motor-evacuation function of the digestive canal. It was found that inhibition of the motor function of the digestive tract in the first three days after surgery led to an increase in the level of intoxication, requiring its mandatory correction. Conclusions. A promising direction in the treatment of patients with acute obstruction of the small intestine is to develop measures that contribute to the preservation, protection and restoration of motility of the digestive tract at all stages of treatment.