Moderate or severe depression and anxiety are prevalent in women with OAB. There is a correlation between intensity of OAB symptoms with depression and anxiety. Anxiety and depression levels are mainly related with urgency incontinence and nocturia.

Mobile WebpISSN 2093-4777 eISSN 2093-6931 INTERNATIONAL NEUROUROLOGY JOURNALPurpose: Overactive bladder (OAB) is characterized by urinary urgency with or without urge incontinence, accompanied by frequency and nocturia. It affects individuals of all ages and can predispose affected individuals to depression and anxiety. However, few studies have been conducted on this topic. The objective of this study was to perform a systematic review and meta-analysis assessing the symptoms of depression, anxiety, and OAB using validated instruments. Methods: The search for articles was based on the following descriptors: overactive bladder, depression, and anxiety ("Urinary bladder, Overactive AND Depression and Anxiety") OR ("Urinary bladder, Overactive AND Depression" OR "Urinary bladder, Overactive AND Anxiety"). The databases searched included PubMed, MEDLINE, and SciELO. Results: Initially, 111 articles were identified, but only 11 articles, containing 11,784 participants with depression and 10,436 with anxiety, specifically addressed depression or anxiety and were included in this systematic review. Ten articles incorporated a quantitative analysis, with cohort, series, population-based, and cross-sectional designs. One qualitative study was also included. Three articles were included in the meta-analysis, resulting in a total of 7,468 participants in whom depression was evaluated and 8,030 participants in whom anxiety was analyzed. Depression and anxiety were positively correlated with OAB. Men with OAB were considerably more likely than women to have anxiety (odds ratio [OR], 1.56; 95% confidence interval [CI], 1.40-1.73) but there was no sex-related difference in depression (OR, 0.96; 95% CI, 0.77-1.21). Conclusions: This study showed a positive correlation between OAB and anxiety and depression. Men were considerably more likely than women to have anxiety related to OAB, but depression levels in OAB patients were not sex-related. This review highlights the need to investigate depression and anxiety in patients with OAB. • HIGHLIGHTS -There was a positive correlation between OAB and anxiety/depression.-Men had more anxiety related to OAB, but depression in OAB patients was not sex-related.-This review highlights the need to investigate depression and anxiety in patients with OAB.

Background Several studies have associated overactive bladder (OAB) with female sexual dysfunction (FSD); however, there are no reports using a quantitative approach to measure OAB severity and to relate OAB to the risk of FSD. Aim To evaluate women with OAB and to correlate the severity of their urinary symptoms with their sexual function. Methods This cross-sectional study included 267 women older than 18 years with untreated OAB. All subjects completed the International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ-OAB) and the Female Sexual Function Index (FSFI). Outcomes Linear regression was used to analyze the association between variables and the numeric FSFI score, and categorical FSFI scores were analyzed using logistic regression. Spearman rank correlation coefficient was used to assess the correlation between ICIQ-OAB results and the different FSFI domains. The significance level was 5%. Results Subjects’ mean age was 50.2 ± 11.9 years. Most women were married, had at least three children, and were postmenopausal (54.3%). Mean FSFI total score was 19.2 ± 9.8. For menopausal status, 65.6% of premenopausal women had a risk for FSD vs 86.2% of postmenopausal women. Mean ICIQ-OAB score was 10 ± 3.17. Postmenopausal women had the following risk factors statistically associated with sexual dysfunction: age, ICIQ score, and marital status. For these women, greater OAB severity, especially those with urgency and/or urge incontinence, was associated with worse scores in the arousal, lubrication, orgasm, and sexual pain domains. However, there was no statistically significant association for premenopausal women. Clinical Implications Health professionals have to pay attention to OAB in women because of the greater risk for FSD in these patients. Strengths and Limitations The strength was using a quantitative approach to measure OAB severity in a larger population. Limitations include a convenience sample with no power calculation; exclusion of women who did not have sexual intercourse in the past month; unmeasured distress caused by sexual disorders; and the impossibility of establishing causality between OAB and sexual dysfunction. Conclusion Women with OAB frequently have a risk for sexual dysfunction. In the postmenopausal group, women with scores indicating severe OAB had worse sexual function, mainly in the arousal, lubrication, orgasm, pain, and total domains.

paixão pelas mulheres e pelas intermináveis divagações psicanalíticas tão necessárias.À família Zavaloni Melotti que são tão especiais, obrigada por fazerem parte de nossas vidas.À minha família de origem, minha mãe, que sempre iluminou meu caminho, ao meu pai Luiz Carlos Ribeiro (in memoriam) pela genética das palavras.Aos meus irmãos, cunhados e sobrinhos, pelo amor e ajuda.Ao meu irmão Iã Paulo, pela revisão do texto.À minha família, meu marido Laércio Zavaloni Melotti pela paciência, pelo amor incondicional e meus filhos, meu mais profundo amor.Às pacientes deste estudo, sem as quais ele não existiria.A DEUS pela vida."A esperança (spes) é uma alegria instável nascida da ideia de uma coisa futura ou passada de cujo desenlace duvidamos em certa medida""O medo (metus) é uma tristeza instável nascida da ideia de uma coisa futura ou passada de cujo desenlace duvidamos em certa medida" "A segurança (securitas) é a alegria nascida de uma coisa passada ou futura sobre a qual não existe dúvida""O desespero (desperatio) é a tristeza nascida de uma coisa passada ou futura sobre a qual não existe dúvida" (ESPINOSA, Éthica IV) RESUMO INTRODUÇÃO: A Bexiga Hiperativa (BH) afeta substancialmente a população feminina em todas as idades. Estima-se que quase metade destas mulheres não procura tratamento adequado para este problema. A depressão e a ansiedade são um conjunto de sintomas que pode surgir em variados quadros clínico e ocorrer como resposta às situações estressantes ou às circunstâncias sociais e econômicas adversas e na presença de doenças crônicas, como a BH. Os transtornos depressivos e a ansiedade são uma das principais causas incapacitantes da população mundial. OBJETIVO: O objetivo deste estudo foi de organizar as evidências disponíveis na literatura acerca das correlações entre os sintomas de Bexiga Hiperativa, depressão e ansiedade na forma de uma revisão sistemática e correlacionar os níveis de depressão e ansiedade (mínima, leve, moderada ou grave) em mulheres com diagnóstico de Bexiga Hiperativa por meio de um estudo de transversal. MÉTODO: A coleta de dados da revisão sistemática foi feita de acordo com o PRISMA Statement -(Preferred Reporting Items for Systematic Reviews and Meta-Analyses). A busca pelos artigos foi baseada nos seguintes descritores: "Overactive Bladder AND Depression Anxiety" or "Overactive Bladder AND Depression" or "Overactive Bladder AND Anxiety". As bases de dados utilizadas foram PUBMED, MEDLINE e Scielo. No estudo de corte transversal foram incluídas 274 mulheres com diagnóstico clínico de BH atendidas no ambulatório de Urologia Feminina do HC-UNICAMP e no ambulatório de Ginecologia Geral do CAISM-UNICAMP, no período de março de 2012 a março de 2015, com poder da amostra de 88,9% para depressão e de 86,2% para ansiedade. Foram utilizados três instrumentos de entrevista: International Consultation on Incontinence Questionnaire Overactive Bladder