Background: The novel coronavirus known as SARS-CoV-2 has spread worldwide and caused the COVID-19 pandemic. In September 2020, more than 32 million confirmed cases of COVID-19, with a death toll of more than 990,000. Among COVID-19 patients, those with cancer had worse outcomes than those without malignancy, but in some studies, the mortality rates differed significantly, ranging from 3.7% to 61.5%. Method: In this descriptive study, survival analysis with the Kaplan Meier curve was used to determine the healing rate of patients with cancer exposed to COVID-19 and undergoing treatment at dr. Moewardi General Hospital Surakarta-Indonesia from February to December 2020, and the Log Rank test was used to analyze data on two related groups. Results: The analysis using the Kaplan Meier method, female patients were found to have a higher survival rate than females, paged less than 50 years had a higher survival rate than those aged > 51 years, breast cancer had the lowest survival rate, and comorbidity of anemia had a higher survival rate than those with other comorbidities. The Log Rank test found a significant difference in the cumulative survival rates of cancer patients with COVID-19 with a p-value of 0.010 for comorbidity types. Meanwhile, from gender (p = 0.632), age (p = 0.672), type of cancer (p = 0.472), there was no significant difference. Conclusion: COVID-19 female patients aged less than 50 years with types of malignancy other than breast cancer and comorbidity of anemia have a higher survival rate..
AbstrakGen deleted in colorectal cancer (DCC) merupakan salah satu gen supresor tumor yang memegang peranan untuk terjadinya keganasan kolorektal. Mutasi gen DCC didapatkan pada 70% kasus dan tidak adanya ekspresi protein DCC ini memberikan prognosis buruk pada kasus keganasan kolorektal. Tujuan penelitian ini adalah untuk mengetahui apakah ekspresi protein DCC berhubungan dengan kemungkinan metastasis keganasan kolorektal.
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