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Appropriate patient selection is essential for achieving clinical success. Better results can be expected in patients with an American Society of Anesthesiologists score of I and when the level managed is confirmed by magnetic resonance imaging and the vertebral body height loss is less than 70%.

The insertion of an implant in the body of a patient raises the risk of a posterior infection and formation of a biofilm, which can have critical consequences on the patient’s health and be associated with a high sanitary cost. While antibacterial agents can be used to prevent the infection, such a strategy is time-limited and causes bacteria resistance. As an alternative to biochemical approaches, we propose here to use light-induced local hyperthermia with plasmonic nanoparticles. This strategy is implemented on surgical meshes, extensively used in the context of hernia repairing, one of the most common general surgeries. Surgical meshes were homogeneously coated with gold nanorods designed to efficiently convert near-infrared light into heat. The modified mesh was exposed to a biofilm of Staphylococcus aureus (S. aureus) bacteria before being treated with a train of light pulses. We systematically study how the illumination parameters, namely fluence, peak intensity and pulse length, influence the elimination of attached bacteria. Additionally, fluorescence confocal microscopy provides us some insight on the mechanism involved in the degradation of the biofilm. This proof-of-principle study opens a new set of opportunities for the development of novel disinfection approaches combining light and nanotechnology.

5G technology will provide networks with high-bandwidth, low latency and multitenancy. The integration of computing and storage resources in the edge of the fronthaul network, i.e., multi-access edge computing (MEC), will allow to instantiate some virtual network functions (VNF) in those computing resources. The backhaul of 5G networks will be based on optical technology, in particular WDM, due to its high capacity and flexibility. In this paper, we analyse the problem of VNF-provisioning in a metro ring-topology network equipped with MEC resources and with a WDM network connecting the edge nodes. In contrast to previous proposals, the method decides where VNFs must be instantiated but also the design of the virtual topology for the WDM metro network in order to reduce the service blocking ratio and the number of resources in operation.