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Background/aim: To investigate the optimal protocol for frozen-thawed embryo transfer (FET) cycles in patients who previously had a cycle cancellation due to uterine peristalsis (UP) Materials and Methods: Thirty-four patients with previous embryo transfer (ET) cancellation due to UP during artificial cycle (AC) were included retrospectively. In the proceeding cycle, endometrium was prepared with AC (n: 23) in AC-FET group or with stimulated cycle that contains letrozole (L) (n: 11) in L-FET group. Intravenous bolus dose of 6.75 mg atosiban (Tractocile; Ferring Pharmaceuticals, Switzerland) injection was performed to all patients of AC-FET group due to UP ≥ 4/min on the planned ET day of proceeding cycle. Atosiban was not used in L-FET group. Primary outcome was live birth rate (LBR) per ET. Secondary outcomes were clinical pregnancy rate (CPR) per ET, implantation rate (IR), cycle cancellation rate.Results: The baseline characteristics as age, body mass index, antral follicle count, duration of infertility and the number of prior in vitro fertilization attempts of each group were similar.The IR, CPR per ET, LBR per ET, CPR per cycle and LBR per cycle were significantly higher; cycle cancellation rates were significantly lower in L-FET group as compared to the AC-FET group.2 Conclusion: Endometrial preparation with letrozole significantly improves CPR and LBR in FET cycles of patients with previous cycle cancellations due to UP.

To evaluate the effects of coronavirus disease-2019 (COVID-19) infection on clinical and laboratory features; maternal and fetal outcomes. Material and Methods: In this retrospective study, the patients diagnosed with COVID-19 by positive severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) reverse transcription polymerase chain reaction (RT-PCR) and delivered at Koru Hospital (Ankara, Turkey) between March 2020 and February 2021 were included. We obtained demographic, clinical, laboratory features, obstetric and delivery history, maternal and perinatal outcomes from medical records. Results: Twelve pregnant patients were included in the study. The mean age was 32 years (range 28-43 years) and the mean gestational age at diagnosis of COVID-19 was 34 weeks (range 22 to 39 weeks 6 days), the mean gestational age at delivery was 38 weeks 4 days (range 35 to 40 weeks). All deliveries were as cesarean section. At first admission with suspicion of COVID-19, seven (58%) patients had fever, five (41%) patients had cough, two (16%) patients had dyspnea, two (16%) patients had anosmia and loss of taste, one (8.3%) patient had sore throat. None of the pregnant patients were taken to the intensive care unit before or after delivery. One neonate was tested for SARS-CoV-2 RT-PCR and the result was negative. Two neonates were admitted to neonatal intensive care unit due to preterm delivery of a twin pregnancy. Conclusion: COVID-19 infection has similar clinical characteristics in pregnant patients as in non-pregnants reported in the literature. The maternal, fetal and neonatal outcomes were good and vertical transmission seems unlikely.