Approximately 75% of the treatment success rate set by the Global Plan to Stop TB was achieved. Resistance to second-line drugs and presence of extensively drug-resistant TB are the main risk factors for poor treatment outcomes.

Wheat–cotton system is a major production system in Pakistan, however, cotton yield is declining in the system most likely due to weeds infestation and intensive tillage practices. Conservation tillage such as reduced and zero tillage in combination with appropriate herbicide may have the potential to enhance cotton yield on sustainable basis. The objective of this study was to determine the effect of herbicides under different tillage systems on weed control and cotton yield in wheat-cotton system. A field experiment was conducted at Cotton Research Station, Ratta Kulachi, Dera Ismail Khan, Pakistan, during 2017 and 2018. In the experiment, post-emergence herbicides, i.e. floxyfop-R-methyl 10.8 EC (108 g a.i. ha-1), lactofen 24 EC (168 g a.i. ha-1), floxyfop 10.8 EC + lactofen 24 EC, hand weeding, weedy check and three tillage systems (zero tillage, reduced tillage and conventional tillage) were evaluated in randomized compete block design (RCBD), with split plot arrangements, replicated 4 times. Tillage was allotted to main plots while herbicides were applied to subplots. The results revealed that hand weeding and floxyfop as post emergence alone or in combination with lactofen reduced weed density to the minimum irrespective of the tillage systems. Maximum dry weed biomass was recorded in control. Interaction effects revealed that reduced tillage in combination with broad spectrum herbicides had maximum weed population reduction percentage. Reduced tillage with broad spectrum herbicides had seed cotton yield compared to zero and conventional tillage. In conclusion, broad-spectrum herbicides under reduced tillage were more productive in wheat based cropping system on silty clay soil of D.I.Khan.

Background: Drug-resistant tuberculosis (DR-TB) is the major cause of mortality worldwide. Our objectives were to determine the distribution of DR-TB by sex, age groups, occupation, province, division, district, type of disease, type of drug resistance, treatment regimen and outcome of treatment in DR-TB population in D.I.Khan Division, Pakistan.Materials Methods: This cross-sectional study was conducted in Department of Community Medicine, Gomal Medical College, D.I.Khan, Pakistan. A sample of 286 DR-TB patients was selected consecutively from population at risk. Sex, age groups, occupation, province, division and district were demographic while type of disease, type of drug resistance, treatment regimen and outcome of treatment were research variables. All variables being nominal were described by count, percentage cumulative percentage with 95% confidence interval for proportion. Distribution of DR-TB patients by all the ten variables were substantiated by chi-square goodness-of-fit test.Results: Out of 286 DR-TB patients, 123 (43%) were men and 163 (57%) women. DR-TB cases were most prevalent in age group 15-44 years 172 (60.14%), housewife 140 (48.95%), Khyber Pakhtunkhwa 175 (61.19%), D.I.Khan Division 178 (62.24%) and district 121 (42.31%). Most common type of disease, drug resistance and treatment regimen was pulmonary TB 282 (98.60%), MDR 273 (95.45%) and longer treatment (n=273 MDR-TB) 246 (90.11%) respectively. Treatment success rate was 161 (56.29%). The observed prevalence by occupation, province, division, district and type of disease in our sample was similar to expected prevalence in population (p.05 for all), while it was different from population by sex, age groups, type of drug resistance, regimen and treatment outcome (p.05 for all).Conclusion: The prevalence of DR-TB was higher in women, age group 15-44 years, housewife, Khyber Pakhtunkhwa and D.I.Khan Division and District. Most common type of disease, drug resistance and treatment regimen was pulmonary TB, MDR and longer treatment respectively. Treatment success rate was 56.29%. The observed prevalence by occupation, province, division, district and type of disease in sample was similar to population, while it was different by sex, age groups, type of drug resistance, regimen and treatment outcome.

Cabbage white butterfly (Pieris brassicae) is one of the important insect pests of cabbage crop which causes remarkable quantitative or qualitative crop losses. The research was conducted at Hazara Agricultural research station, Abbottabad (Pakistan) to study the effect of different new chemical insecticides, botanical oil and neem seed oil (Azadirachta indica A. Juss.) on the population density of P. brassicae. The study showed that neem oil had a significant effect on population of P. brassicae in comparison to control treatment. So, neem oil alone or in combination with insecticides can be used for control of P. brassicae in vegetable crops for a safer food supply.