INTRODUCTION:Various quality improvement (QI) interventions have been individually assessed for quality of cardiopulmonary resuscitation (CPR). We aimed to assess QI bundle (hands-on training and debriefing) for quality of CPR in our children's hospital. We hypothesized that QI bundle improves quality of CPR in hospitalized children. METHODS:We initiated a QI bundle (hands-on training and debriefing) in August 2017. We conducted a before-after analysis comparing the CPR quality during July 2013-May 2017 (before) and January 2018-December 2020 (after). We collected data from the critical events logbook on CPR duration, chest compressions (CC) rate, ventilation rate (VR), timing of first epinephrine, blood pressure (BP), end-tidal CO2(EtCO2) and vital signs monitoring during CPR. We performed univariate analysis and presented data as median interquartile range (IQR) and in percentage as appropriate. We compared the groups using Chi-Square test (significant p< 0.05).

Introduction. Various quality improvement (QI) interventions have been individually assessed for the quality of cardiopulmonary resuscitation (CPR). We aimed to assess the QI bundle (hands-on training and debriefing) for the quality of CPR in our children’s hospital. We hypothesized that the QI bundle improves the quality of CPR in hospitalized children. Methods. We initiated a QI bundle (hands-on training and debriefing) in August 2017. We conducted a before-after analysis comparing the CPR quality during July 2013–May 2017 (before) and January 2018–December 2020 (after). We collected data from the critical events logbook on CPR duration, chest compressions (CC) rate, ventilation rate (VR), the timing of first dose of epinephrine, blood pressure (BP), end-tidal CO2 (EtCO2), and vital signs monitoring during CPR. We performed univariate analysis and presented data as the median interquartile range (IQR) and in percentage as appropriate. Results. We compared data from 58 CPR events versus 41 CPR events before and after QI bundle implementation, respectively. The median (IQR) CPR duration for the pre- and post-QI bundle was 5 (1–13) minutes and 3 minutes (1.25–10), and the timing of the first dose of epinephrine was 2 (1-2) minutes and 2 minutes (1–5), respectively. We observed an improvement in compliance with the CC rate (100–120 per minute) from 72% events before versus 100% events after QI bundle implementation ( p = 0.0009 ). Similarly, there was a decrease in CC interruptions and hyperventilation rates from 100% to 50% ( p = 0.016 ) and 100% vs. 63% ( p = < 0.0001 ) events before vs. after QI bundle implementation, respectively. We also observed improvement in BP monitoring from 36% before versus 60% after QI bundle ( p = 0.014 ). Conclusion. Our QI bundle (hands-on training and debriefing) was associated with improved compliance with high-quality CPR in children.

Epilepsy with myoclonic absence (EMA) is a rare disorder with a mean age of onset of 7 years. It is characterized clinically by rhythmic, myoclonic jerking of the head, extremities or both, with impairment of consciousness and an ictal electroencephalogram (EEG) pattern of 3 Hz bilateral, synchronous and symmetrical spike and wave discharges. Prognosis is guarded and most patients are pharmaco-resistant. We present a case of EMA, found to have a FOXP1 gene pathogenic variation and a variance of unknown significance in the MBD5 gene, who was admitted to the intensive care unit in super-refractory status epilepticus. Given the overlap in symptoms of syndromes including myoclonic-astatic epilepsy, childhood absence epilepsy and juvenile myoclonic epilepsy, a detailed seizure semiology with EEG correlation, cannot be over emphasized. In this case, the genetic etiology may lend an interesting insight to the severity and prognosis.

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