Background and Aims: Laparoscopic surgery is nowadays gold standard procedure undertaken for various surgical procedures and people prefer laparoscopic approach but the effective analgesic regimen for such patients has not been devised and anaesthesiologists prefer multimodal regimes. Despite the minimally invasive nature of this procedure, patients experience a considerable amount of pain in the first 24 h postoperatively. In our study, we are comparing the  degrees of pain relief with TAP block vs Trocar site infiltration using VAS, the duration of postoperative analgesia achieve by   TAP block and compare it with Trocar site infiltration and  total consumption of rescue analgesia consumed in first 24 hours postoperatively in patients undergoing gynaecologic  Laparoscopic surgeries. Methods: After obtaining approval from the hospital Ethical committee and written informed consent from patients, this observational study was undertaken at the Government Lalla Ded Hospital which is one of the associated hospitals of Government Medical College, Srinagar during routine hours on 100 patients posted for elective Gynecological Laparoscopic surgery under general anesthesia.  A total sample size of 100 patients (n= 50) for each group was calculated using PASSE (power and sample estimation) for study design and analysis. Assuming 30% improvement in pain score with error of 0.05 (i.e. 5% of DOF   (degree of freedom). Results: Visual analogue scale at different time intervals were statistically significantly lower at all times in Group A than Group B p-value (p<0.05). The time to first request for analgesia was higher in group A as compared to group B   with statistical difference among the study groups  p-value (p<0.05). Conclusion: As a promising novel post-operative pain treatment procedure, TAP block is cost effective and one of the safest, easiest and the most effective supplemental techniques as part of analgesic regimen. It improves pain scores in gynecologic laparoscopy.

Postoperative pain following laparoscopic cholecystectomy is one of the main causes for lengthening the period of hospitalization. In an attempt to decrease this early postoperative complication, esmolol infusion was administered during general anaesthesia to patients undergoing laparoscopic cholecystectomy. Sixty patients ASA class I undergoing laparoscopic cholecystectomy were randomly assigned to two groups, esmolol group (Group E, n=30) and placebo group (Group P, n=30). In group E, patients received 1mg/kg esmolol bolus dose i.v immediately before induction while as group P received same volume of inj. Ringer Lactate as placebo. In group E, immediately after intubation, esmolol infusion was started at the rate of 5-10 µg/kg/min. The rate was titrated to maintain heart rate between 65-75 beats per min. Patients in group P received 100 ml of Ringer Lactate infusion. The incidence of PONV and pain were assessed after surgery. Incidence of postoperative analgesia requirement was significantly less in esmolol group. 50% of patients required analgesia in group E, while 83.33% required analgesia in group P (p=0.006). Post operative antiemetic requirements were also significantly less in group E. It was concluded that incidence of postoperative analgesia requirements over first 24 hours after laparoscopic cholecystectomy was found to be less in esmolol group as compared to placebo group.