The present study shows that low serum magnesium levels in children and adolescents with T1DM are associated with an increased risk of poor glycemic control, potentially contributing to the early development of cardiovascular complications.

Floating-Harbor syndrome (FHs) is a very rare condition of unknown etiology characterized by short stature, delayed bone age, characteristic facial features, delayed language skills and usually normal motor development. this syndrome has only once been associated with growth hormone deficiency and precocious puberty in the same patient. We describe a 5 4 /12 year-old girl with the typical features of FHs in whom growth hormone deficiency was diagnosed and two years later central precocious puberty was noted. the patient showed a good response to human recombinant growth hormone as well as gonadotropin releasing hormone analogue treatment.

The prevalence of selective IgA deficiency in Greek children and adolescents with T1D is high (3.0%). The correlation of serum IgA concentrations with serum IgG, IgE and anti-gliadin antibody IgG concentrations needs further investigation.

This study shows that obesity in youngsters, when accompanied with insulin resistance, is associated with at least threefold increased risk for elevated levels of prothrombotic factors, contributing to the early development of atherothrombosis. This impaired prothrombotic state may partially explain the increased risk for developing cardiovascular disease later in adulthood.