Prostate intratumoral heterogeneity, driven by epithelial–mesenchymal plasticity, contributes to the limited treatment response, and it is therefore necessary to use the biomarkers to improve patient prognostic survival. We aimed to characterize the tumor microenvironment (T lymphocyte infiltration, intratumoral CD34, and KI-67 expressions) by immunohistochemistry methods and to study the biological mechanisms (cell cycle, cell proliferation by adhesion glycoproteins, cell apoptosis) involved in the evolution of the prostate tumor process by flow-cytometry techniques. Our results showed that proliferative activity (S-phase) revealed statistically significant lower values of prostate adenocarcinoma (PCa) and benign prostatic hyperplasia (BPH) reported at non-malignant adjacent cell samples (PCa 4.32 ± 4.91; BPH 2.35 ± 1.37 vs. C 10.23 ± 0.43, p < 0.01). Furthermore, 68% of BPH cases and 88% of patients with PCa had aneuploidy. Statistically increased values of cell proliferation (CD34+ CD61+) were observed in prostate adenocarcinoma and hyperplasia cases reported to non-malignant adjacent cell samples (PCa 28.79 ± 10.14; BPH 40.65 ± 11.88 vs. C 16.15 ± 2.58, p < 0.05). The CD42b+ cell population with a role in cell adhesion, and metastasis had a significantly increased value in PCa cases (38.39 ± 11.23) reported to controls (C 26.24 ± 0.62, p < 0.01). The intratumoral expression of CD34 showed a significantly increased pattern of PCa tissue samples reported to controls (PCa 26.12 ± 6.84 vs. C 1.50 ± 0.70, p < 0.01). Flow cytometric analysis of the cell cycle, apoptosis, and adhesion glycoproteins with a critical role in tumoral cell proliferation, T cell infiltrations, Ki-67, and CD 34 expressions by IHC methods are recommended as techniques for the efficient means of measurement for adenocarcinoma and hyperplasia prostate tissue samples and should be explored in the future.

In 105 cases the posterior ramus originated from a renal artery bifurcated into anterior and posterior branches and in 78 cases from trifurcated renal artery. In 12 cases, the posterior ramus originated from a renal artery terminated with four branches. From the aorta, as supernumerary renal artery, the posterior branch originated in 7 cases, 3 cases as double and 4 cases as triple renal arteries. In 86 cases the posterior ramus originated from the anterior branch of the renal artery, superior or inferior or both. the arcade aspect was found in only 134 cases. A particular aspect of the arch is the italic "S" (or inverted italic "S") or double arch, which we found in 24 cases. this type of posterior branch supplied the entire posterior valve, an aspect found in 11 cases. When the posterior branch was not in arcade, it was arranged transversally and ended by bi or trifurcation. the ending by bifurcation was found in 113 cases and by trifurcation in 17 cases. All of these cases, both the right and the left, supplied the entire posterior valve. In all cases, regardless of any aspect of the posterior branch, it supplied the entire posterior valve in 88 cases. the posterior branch supplied the superior pole in 250 cases, the inferior one in 181 and only the posterior mesorenal part, without participating in the supply of the two poles, in 233 cases.

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