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SUMMARY The psychiatric histories in a group of patients who had previously undergone temporal lobectomy for intractable epilepsy, were analysed for the occurrence of psychosis. The data suggest that epileptic patients with left temporal lobe lesions are especially disposed to develop a schizophrenic-like psychosis.In an earlier study of patients selected for the concordance of medically intractable epilepsy and behaviour disorder, we reported that 15 % of the patients demonstrated a schizophrenic-like psychosis at some point in their illness.' All of the psychotic patients appeared to have had left temporal lobe epileptogenic lesions (TLEL) based on pneumoencephalographic and electroencephalographic (EEG) findings. It is difficult to establish a relationship between a type of psychiatric illness and the laterality of an epileptogenic lesion, for conventionally recorded EEG, or even depth recorded interictal data,2 3 are unreliable. We have examined the relative frequency of psychosis in a group of patients with unilateral epileptogenic lesions established by depth recorded ictal episodes, so as to justify a temporal lobectomy. Patients and methodsDetails of the evaluation of these patients for possible "seizure-surgery" have been reported elsewhere.4 In those patients in whom a unilateral temporal lobe lesion was identified, Dr Paul Crandall performed an en bloc anterior temporal lobectomy, which extended only I cm more posteriorly in the minor *

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