Abstract:Two experiments were conducted with a view to evaluating the Somaticell® diagnosis involving an indirect somatic cell-count in buffalo milk. In experiment A, six Murrah buffaloes in different lactation phases were subjected to Somaticell®, CMT and Alizarol tests. In experiment B, 49 Murrah buffaloes in different lactation phases were used, giving a total of 196 samples, on which Somaticell® and CCS tests were carried out using an electronic counter. It was observed that the counting of somatic cells performed using Somaticell® provided values significantly higher than those obtained when using an electronic counter. The values obtained using the Somaticell® test were 4.7 times higher than those obtained for the same samples by way of electronic counting of somatic cells. Comparison of Somaticell® and CCS electronic counting for each mammary gland separately revealed a disparity between the mean values obtained using both techniques, with the lowest values obtained using Somaticell® 69 times higher than those obtained using CCS. The correlations between both tests were low and insignificant, demonstrating that the techniques behave differently when counting the somatic cells in buffalo milk.Viana et al. / Rev. Ci. Agra., v.53, n.