BACKGROUND <br />Menopause is a condition in which the menstrual periods have stopped for the last 12 months due to cessation of ovarial functions causing estrogen hormones to decrease. Various studies find that many factors affect cognitive function at post-menopausal age among others the decrease in estrogens, age at menopause, duration of menopause, and education. However, the effects have been subject to controversy. The aim of this study was to determine the relationship of age, age at menopause, estradiol level, and education with cognitive function among healthy post-menopausal women. <br /><br />METHODS <br />A cross-sectional study was conducted involving 31 post-menopausal women between 50 to 75 years old. Data on age, age at menopause, and education were collected using a questionnaire. The estradiol levels were measured using an electrochemiluminescent immunoassay (ECLIA). The Indonesian version of the Montreal Cognitive Assessment (MoCA INA) was used to assess the cognitive function. Multiple linear regression was used to analyze the data. A p&lt;0.05 was considered statistically significant.<br /><br />RESULTS <br />Age (b=-0.086; 95% C.I.=-0.263-0.090; p=324) and estradiol levels (b=0.106; 95% C.I.=-0.018 -0.230; p=0.092) were not significantly associated with cognitive function. However, education (b=1.537; 95% C.I.=0.176-2.898; p=0.028) and age at menopause (b=0.364;0.056-0.671; p=0.022) were significantly associated with cognitive function. Age at menopause was the most influential factor of cognitive function (Beta=0.402) compared to education (Beta=0.394).<br /><br />CONCLUSION <br />Later age at menopause could increase cognitive function in post-menopausal women. Our findings are that modifiable factors that delay age at menopause should receive attention, in order to promote cognitive function. <br /><br />Keywords: Age at menopause, estrogens, cognitive function, post-menopausal women

Latar Belakang: Merokok adalah masalah Kesehatan masyarakat utama diseluruh dunia termasuk Indonesia. Perokok pasif (orang yang terpapar asap rokok) terpapar zat yang sama seperti perokok aktif, yaitu termasuk tar, nikotin, karbon dioksida, karbon monoksida, dan hidrokarbon aromatik polisiklik Paparan asap rokok pada wanita hamil yang tidak merokok dapat menyebabkan gangguan pada kehamilan salah satunya adalah berat badan lahir bayi rendah (BBLR)Tujuan Penelitian: Menentukan adanya hubungan wanita hamil perokok pasif dengan kejadian BBLRMetode yang digunakan adalah studi analitik dengan desain Cross Sectional. Cross sectional merupakan desain studi yang bersifat observasi dimana penelitian tersebut hanya  pengambilan data dilakukan hanya sekali saja pada setiap responden. Penelitian akan dilakukan di beberapa puskesmas di Jakarta Timur pada November 2017 sampai Desember 2017. Populasi pada penelitian ini merupakan wanita yang melahirkan bayi secara aterm di  beberapa puskesmas di Jakarta Timur pada Januari hingga Juni 2017, didapatkan 132 Subjek. Subjek dipilih jika memenuhi kriteria inklusi dan eksklusi dengan menggunakan teknik consecutive sampling. Bahan penelitian menggunakan data primer yaitu kuesioner dan data sekunder yaitu rekam medis. Analisis univariat disajikan dalam bentuk tabel dan narasi. Analisis bivariat menggunakan uji Chi-square untuk mendapatkan nilai probabilitas wanita hamil perokok pasif dan BBLR dengan menggunakan derajat kepercayaan (CI) 95% dan tingkat kemaknaan < 0,05.Pada studi ini berdasarkankan uji statistik chi-square didapatkan p = 0,492, yang berarti tidak ada hubungan bermakna antara ibu hamil perokok pasif dengan kejadian berat badan lahir rendah

Latar Belakang: Gangguan kesehatan yang terjadi selama kehamilan dapat mempengaruhi kesehatan janin dalam kandungan hingga kelahiran dan pertumbuhan bayi selanjutnya. Antropometri pada bayi baru lahir dapat dipengaruhi oleh beberapa faktor yaitu anemia pada kehamilan, nutrisi maternal yang kurang, infeksi maternal dan fetal, dan ibu mengandung janin multipel. Anemia pada wanita hamil akan meningkatkan risiko mortalitas dan morbiditas perinatal karena dapat menyebabkan gangguan nutrisi dan oksigenasi utero plasenta yang menimbulkan gangguan pertumbuhan hasil konsepsi.Tujuan: Penelitian ini bertujuan untuk menilai hubungan anemia pada ibu hamil dengan antropometri bayi baru lahir.Metode: Analisis observasional dengan desain studi potong lintang dengan subjek penelitian ibu hamil yang melahirkan di RS pada bulan Januari 2017 - Juni 2018. Variabel yang dikumpulkan dan akan diteliti adalah kadar Hb trimester III, berat badan bayi lahir, panjang badan bayi lahir, dan lingkar kepala bayi lahir yang diperoleh dari data sekunder yaitu rekam medis.Hasil dan Pembahasan: Total subjek pada penelitian ini adalah 152 subjek, sebagian besar subjek penelitian berusia 26 - 30 tahun (41,4%) dengan ibu tidak anemia sebanyak 105 orang (69,1%). Hasil analisis menunjukkan tidak ada hubungan antara berat badan bayi baru lahir dengan anemia pada ibu hamil, tidak ada hubungan antara panjang badan bayi baru lahir dengan anemia pada ibu hamil, ada hubungan antara lingkar kepala bayi baru lahir dengan anemia pada ibu hamil.Kesimpulan: Penelitian ini menunjukkan bahwa terdapat hubungan bermakna antara anemia pada ibu hamil dengan lingkar kepala bayi baru lahir (p = 0,050), tetapi didapatkan tidak terdapat hubungan bermakna antara anemia pada ibu hamil dengan berat badan bayi lahir (p = 0,374) dan panjang badan bayi lahir (p = 0,198). Kata Kunci : Anemia; Ibu Hamil; Hemoglobin trimester III; Antropometri bayi

Background<br />Cerebrovascular disease occurs due to atherosclerosis of the carotid artery triggered by endothelial dysfunction, which can be assessed by measuring the carotid intima-media thickness (CIMT). There are several risk factors contributing to endothelial dysfunction, such as 25-hydroxyvitamin D [25(OH)D] deficiency. A number of research studies have shown variable results on the relationship between 25(OH)D deficiency and endothelial dysfunction. The objective of the present study was to determine the relationship between 25(OH)D and CIMT in elderly women.<br /><br />METHODS <br />A cross-sectional study was conducted involving 45 elderly women aged ≥60 years. The inclusion criteria were: able to communicate well and able to walk actively without any help. The exclusion criteria were: not having diabetes mellitus, stroke, heart disease, kidney disease, not consuming vitamin D or medicines containing corticosteroids, and not using hormone replacement therapy. Laboratory examination was conducted for fasting blood sugar, lipid profile, and 25(OH)D. CIMT was measured using carotid Doppler ultrasonography at the left carotid artery. Simple linear regression analysis was used to analyze the data.<br /><br />RESULTS<br />Mean 25(OH)D level was 11.753 ± 4.027 ng/mL, and mean CIMT 0.61 ± 0.10 mm. Simple regression analysis showed a significant relationship between 25(OH)D level and CIMT (β=-0.001; 95% C.I.=-0.020-0.003; p=0.009).<br /><br />CONCLUSION <br />Our data suggest an inverse association between 25(OH)D level and CIMT in elderly women. This study supports the protective role of vitamin D against subclinical atherosclerosis in elderly women.

Background and Aims. Maternal Mortality Rate (MMR) is the parameters of women's health status in community. The single most common cause of maternal mortality is obstetric haemorrhage, generally occurring postpartum. Most postpartum haemorrhage cases are caused by uterus atony, myometrium tonus loss, placenta retention, and clotting disorders. Short pregnancy intervals can cause threefolds of anaemia than normal pregnancy intervals. Pregnant women who suffer from anaemia has the possibility experiencing a postpartum bleeding caused by atonia uteri. This research aims to acknowledge the effect of narrow distance interpregnancy on a postpartum haemorrhage. Methods. This study uses an observational analytic study with a cross"‘sectional design. The data used is secondary data of pregnant women based on medical record to calculate the distance of interpregnancy with the incidence of postpartum bleeding during childbirth at Budhi Asih General Hospital of East Jakarta. The inclusion criteria are women who underwent childbirth during 2017"‘2018, multiparity, and postpartum women between 20"‘35 years old. The exclusion criteria are women with a history of postpartum haemorrhages caused by placental retention, tear of the reproductive tract or blood coagulation), gemelli parturition, macrosomia, assisted childbirth, grande multiparity, induction childbirth, and dystocia. Results. The number of samples used in this study amounted to 111 people. Postpartum haemorrhage are significantly associated with short interpregnancy intervals (p=0,000). Conclusion. Narrower pregnancy interval will leads to postpartum haemorrhage. To prevent this, it is important to consider contraception utilization, to improve iron consumption for pregnant women, and to provide decent antenatal care.