This study aims to analyze the scientific evidence regarding the management of the Sepsis Protocol from an integrative literature review. This question guided a search in the electronic databases: SciELO, MEDLINE, LILACS and PubMed, all present in the Virtual Health Library and Web of Science. Ten publications were analyzed, from 2017 to 2021. Most of the results indicate that sepsis management is necessary to improve patient management, rapid identification of signs and symptoms and contribute to increasing the effectiveness of the multidisciplinary team. It is concluded that sepsis is a serious pathology, which affects most patients admitted to the Intensive Care Unit. It shows the need for hospital services to standardize and institute sepsis management protocols, since there are currently many existing control mechanisms, involving increasingly sophisticated and low-cost technologies. I.Therefore, the relevance of this article lies in the need to discuss scientific advances regarding the management of sepsis, whose objective is to analyze the scientific Cordeiro et al.

This study aims to evaluate the prevalence of sepsis in a public maternity hospital in the Eastern Amazon. This is a descriptive, retrospective cross-sectional study with a quantitative approach, carried out with data from 135 medical records of patients affected by sepsis in a referral hospital, in 2021. The data were tabulated in the Statistics Program for Social Science for Windows (SPSS® 16.0) software. , SPSS Inc, Chicago, IL, USA) and the research complied with Resolution No. 466/12 of the National Health Council, which regulates research with human beings. The results show sepsis predominant in females (82.96%), aged 19 to 29 years (48.15%), coming from the capital Belém, from the obstetric clinic (62.22%), with a focus of pulmonary infection (37 .78%), organ dysfunction characterized by Systolic Blood Pressure < 90 mmHg or MAP < 65 mmHg or BP drop > 40 mmHg (56.30%), with sepsis outcome (75%) and tachycardia symptom (88.15%). It is concluded that this study contributed to the knowledge of the sepsis profile, and consequently to the assessment of the need to implement new health practices.

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