No abstract

No abstract

To the Editor, Studies looking specifically at the prevalence of eosinophilic phenotypes in mild asthma are required. In patients with corticosteroidnaïve asthma, we reported that high eosinophil counts do not necessarily translate into clinical symptoms or lower lung function. 1 However, in asthma of all severities, eosinophils are linked to the worst outcomes. 2 As such, early identification of mild/very mild asthma patients with significant eosinophilia could be a marker of increased risk of such events to modulate therapeutic intervention.This study aimed to compare the features of eosinophilic and non-eosinophilic asthma in patients with asthma of various severities and compare the characteristics of patients according to the intensity of eosinophilia. We hypothesized that patients with an eosinophilic phenotype would demonstrate a more active form of the disease, regardless of its severity.We conducted a retrospective, cross-sectional study based on data from subjects included in the Quebec Heart and Lung Institute-Laval University asthma databank between March 1999 and June 2017. All subjects enrolled for participation in research studies on asthma pathophysiology or treatment, or attending the asthma out-