Summary. FXIIIB phenotypes were determined in neuraminidase-pretreated serum samples by using isoelectric focusing in ultrathin-layer polyacrylamide gels containing 1 M urea and subsequent immunoblotting. In a Libyan population sample from Tripoli, (n = 108) nine different phenotypes as products of four common alleles were recognized, with frequencies as follows: FXIIIB*I = 0.6574, FXIIIB*2 = 0.2454, FXIIIB*3 = 0.0741 and FXIIIB*6 = 0.0231. It is suggested that FXIIIB*6 is the fourth common allele of the FXIIIB system in this population.Key words: Coagulation factor XIIIB, Genetic polymorphism in LibyansAllele FXIIIB*6Zusammenfassung. Der genetisch determinierte Polymorphismus des FXIIIB wurde durch isoelektrische Fokussierung in ultradtinner Schicht eines Harnstoff-haltigen Polyacrylamidgels mit anschliegendem Immunoblott dargestellt. Die Serumproben wurden vor der Verimpfung mit Neuraminidase behandelt. Bei Libyern aus Tripoli (n = 108) wurden die neun h~iu-figen Phfinotypen FXIIIB 1-1, 2-1, 3-1, 2-2, 3-2, 3-3, 6-1, 6-3 und 6-6 beobachtet. Folgende Allelfrequenzen wurden ermittelt: FXIII*I = 0,6574, FXIIIB*2 = 0,2454, FXIIIB*3 = 0,0741 und FXIIIB*6 = 0,0231. Es wird vermutet, dab das Allel FXIIIB*6 das vierte, h~iufige (allgemeine) Allel in dieser Population darstellt.
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