Material and Methods: This was an experimental study with posttest only control group design approach. Purposive technique is applied to collect samples which are lower molar extraction forceps. In this study, sample were divided into 2 groups and each consisting of 18 instruments. The treatment group was treated with 2% glutaraldehyde while the control group was treated with 4.8% chloroxylenol. Each instrument was pre-cleaned using a brush, water and soap for both groups underwent the disinfection process. Results: The results were statistically analyzed using Mann-Whitney Test. The comparison between glutaraldehyde and chloroxylenol showed a significant difference to the total bacteria count on instrument after disinfection (p=0.014 < 0.05). Conclusion: 2% glutaraldehyde was more effective than 4.8% chloroxylenol at disinfecting lower molar extraction forceps.

Objective: To compare Chloroxylenol 4.8% and Povidone Iodine 7.5% on total bacterial count post WHO routine hand washing on clinical students at the department of oral surgery, Faculty of Dentistry, Universitas Sumatera Utara Material and Methods: This was an experimental study with posttest only control group design approach. Purposive technique is applied to collect samples which are clinical students. In this study, sample were divided into 3 groups and each consisting of 10 people. Aquadest was used as control group while Chloroxylenol 4.8% and Povidone Iodine 7.5% was used as the treatment group. Each member performed routine handwashing using WHO method for 1 minute long. Results: The results were statistically analyzed using Kruskal Wallis and Mann-Whitney Test. The comparison between Chloroxylenol and Povidone Iodine showed no significant difference to the total bacteria count after handwashing (p>0.05) but the Chloroxylenol group showed a greater mean reduction. Conclusion: Chloroxylenol and Povidone Iodine are capable reducing the number of bacteria in hands, therefore it can be a good antiseptic choice for hand washing.

Material and Methods: This is an experimental research with a post-test only approach. The sampling technique used is Purposive Sampling. In this study, sample were divided into 2 groups consisting of 18 extraction instruments which are lower molar forceps rubbed with 70% alcohol and soaked in 70% alcohol. Each instrument were pre-cleaned using brush, water and soap prior disinfection process. Results: The results were statistically analyzed using Mann-Whitney Test. The result showed no significant difference to the total bacteria count on rubbing and soaking using 70% alcohol. Conclusion: Soaking in 70% alcohol method showed more effective because it overally kills bacteria.

Oral cancer account for 30% of all malignant tumors in the head and neck, more than 90% of these cancers are squamous cell carcinoma. The p53 tumor suppressor gene known as "the guardian of the genome" has a major function in cell cycle control and act as a main defense against cancer, the occurrence of genomic instability causes inactivation and mutation of p53, which related to the progression of cancer cells and poor prognosis for patients. Human telomerase reverse transcriptase (hTERT), a catalytic protein subunit of the complex telomerase enzyme, prevents telomere erosion during DNA replication, thus allowing cells to escape the aging cell step. The relationship between hTERT and malignant transformation is around 90%, the detection of hTERT is associated with malignancy that leads to a worse prognosis which increases immortality or continuous growth in cancer cells. This study was conducted with retrospective cross sectional using immunohistochemical p53 and hTERT smear in 30 paraffin blocks of squamous cell carcinoma of the oral cavity, held at the Anatomical Pathology Department of Hasan Sadikin Hospital Bandung. P53 and hTERT immunoexpression were correlated with histopathological grading of squamous cell carcinoma of oral cavity (SCC) and statistically analyzed with Rank Spearman correlation with significance of p<0.05 (95%) and Kendall Coefficient of Concordance with significance of p <0.05% (95%). The results showed a significant positive correlation between p53 immunoexpression with histopathological grading (rs=0.497, p-value = 0.005), between hTERT immunoexpression and histopathological grading (rs=0.441, p-value=0.015), and between p53 and immunoexpression hTERT with histopathological grading (W=0.568, p-value=3.99E-08) Conclusion: the higher p53 and/or hTERT immunoexpression, the higher or worse the level of histopathological grading of oral cavity squamous cell carcinoma (poorly differentiated).

After tooth extraction, dentists always place sterile tampons on the extracted socket to stop bleeding, to prevent infection and to reduce patients’ discomfort. Ozone is a biocompatible, bactericidal gas that can accelerate the healing of wounded soft tissue. In addition, it comes up with hemostasis effect to stop bleeding and may accelerate the clotting time and wound healing. Another advantage of ozone therapy is that it can be treated without making any trauma. The purpose of this research is to evaluate the effectivity of ozone water application in the socket to accelerate clotting time phase after posterior teeth extraction in 3 minutes, 6 minutes, and 10 minutes. This research was clinical experimental research with post-test only control group design. The research sampling was done through non-probability sampling. Then, sample was divided into two groups, each of which consisted of 15 patients treated with ozone tampons and 15 patients treated with sterile tampons after tooth extraction. Data were analyzed using chi-square test, and results showed a significant difference between the two groups. Ozone tampons show better result in accelerating clotting time after posterior teeth extraction than sterile tampons.