The article presents the evaluation of curative and preventive efficacy of the anticoccidial drug "Coccimax" in a joint application of the feed additive "Mintov" and "NitaminOR Active", in experimental coccidiosis of chickens. For this purpose, the morphological and biochemical parameters of the blood of broiler chickens were analyzed. Based on the work done, it was concluded that with the development of chicken eimeriosis, there is a negative effect on the liver of birds, expressed by an increase in the activity of aspartate aminotransferase. However, the drug "Coccimax", both when mono used, and when combined with feed additives "Mintov" and "NitaminOR Active", contributes to the normalization of this indicator in comparison with the control group.

The article presents the evaluation of curative and preventive efficacy of the anticoccidial drug “Coccimax” in a joint application of the feed additive “Mintov”, in experimental eimeriosis of chickens. Were determined the degree of infection and the dynamics of changes in body weight in the experimental bird. It was found that the use of the anticoccidium drug “Coccimax” together with the feed additive “Mintov” helps to reduce the infestation of chickens (at the end of the experiment, the infection of birds in the control group was higher by 90-91 % compared to the experimental groups), provides increased survival rate (by 13.3% compared to the control group) and body weight gain (by 8.5–11.8 % compared to the control group).

The article presents the evaluation of the medical-prophylactic efficacy of the anticoccidial preparation Coccimax in a joint application of the feed additive Nitamin OR Active, in experimental eimeriosis of chickens. Were determined the degree of infection and the dynamics of changes in body weight in the experimental bird. It was found out that the use of the anticoccidium preparation Coccimax in combination with the feed additive Nitamine OR Active reduces the infestation of chickens (at the end of the experiment, the infection of birds in the control group was higher by 81 - 90 % compared to the experimental groups), provides increased survival rate (by 13.3% compared to the control group) and body weight gain (by 11.8-17.8% compared to the control group).

The common practice in the prevention and treatment of eimeriosis in chickens is the application of anticoccidial preparations. The parameters of acute toxicity of the anticoccidial preparations Decvycox in laboratory animals were studied. It was found out that the LD50 of Decvycox with oral administration to mice and rats exceeds doses of 6579 and 7222 mg/kg of animal weight, respectively. Thus, according to the generally accepted hygienic classification, Decvycox belongs to hazard class 4 - low-hazard substances.