The CAMCOG discriminated controls and MCI from demented patients, but was less accurate to discriminate MCI from controls. The best cut-off value to differentiate controls and demented was higher than suggested in the original publication, probably because only cases of mild to moderate dementia were included. This is important given the need for a diagnostic at earlier stages of Alzheimer's disease.
ResumoDiscute-se neste artigo de revisão a relação entre demência e autonomia, com enfoque particular nas perdas cognitivas e no comprometimento da memória. A doença de Alzheimer (DA) é uma doença neurodegenerativa progressiva que provoca demência, comprometendo, ao longo de sua lenta evolução, a autonomia dos pacientes. A redução da autonomia é o fator determinante da dependência de um cuidador, que se torna indispensável para preservar o provimento das necessidades básicas da vida diária do paciente. É feita uma distinção entre a dependência por limitações motoras e redução de mobilidade, daquela decorrente das perdas cognitivas. Discute-se também a importância do uso racional dos instrumentos de rastreio cognitivo e avaliação funcional na mensuração do grau de autonomia dos indivíduos acometidos.Palavras-chave: doença de Alzheimer, autonomia, qualidade de vida, memória, teste cognitivo, escala funcional.
AbstractAlzheimer disease (AD) is a progressive neurodegenerative disorder that leads to cognitive impairment and dementia. Within a global reduction in cognitive skills, the loss of memory-related functions has a pivotal role in the development of functional disability. As opposed to physical handicap, disability due to cognitive impairment is a strong determinant of reduced autonomy, which in turn determines the degree of dependency on a caregiver. We further discuss the role of functional and cognitive screening instruments in the assessment of the degree of autonomy in patients with dementia.
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