A terapia de ressincronização cardíaca (TRC) surgiu como modalidade terapêutica para pacientes com insufi ciência cardíaca (IC) refratária ao tratamento farmacológico. Ao longo dos últimos 20 anos, vários estudos clínicos buscaram estabelecer seus benefícios em diferentes populações. A revisão dos resultados desses estudos demonstrou que em pacientes com IC avançada [classes funcionais (CFs) I, II, III e IV da New York Heart Association (NYHA)] a TRC produz melhorias consistentes para a qualidade de vida, CF e capacidade de exercício, além de reduzir as hospitalizações e a taxa de mortalidade. Até 70% dos pacientes submetidos à TRC evoluem como respondedores. Os critérios adotados na avaliação da taxa de resposta à TRC serão elucidados neste artigo, no qual o objetivo maior é ressaltar o conceito do super-respondedor à TRC.
Cardiac resynchronization therapy (CRT) emerged as a therapeutic modality for patients with cardiac insufficiency (CI) refractory to pharmacological treatment. Over the last 20 years, several clinical studies have sought to establish their benefits in different populations. The review of the results of these studies has shown that in patients with advanced CI (functional class (FC) I, II, III and IV of the New York Heart Association (NYHA) CRT produces consistent improvements in quality of life, FC and exercise capacity, as well as reducing hospitalizations and mortality rates. Up to 70% of patients submitted to CRT evolve as responders. The criteria adopted in the evaluation of the CRT response rate will be elucidated in this article, in which the main objective is to highlight the concept of the CRT super-responder.
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