Background: Use of saliva as a specimen for detection of antibodies to infectious agents has generated particular interest in AIDS research community since 1980s. HIV specific antibodies of immunoglobulin isotypes IgA, IgG, and IgM are readily found in salivary secretions. Aim and Objectives: In the present study, HIV specific antibodies were detected in saliva and serum samples of HIV patients by ELISA in confirmed HIV seropositive patients and efficacy of saliva was established in diagnosis of HIV. Methods: The 100 saliva and serum samples were collected from age and sex matched confirmed HIV seropositive subjects and 100 Healthy Controls without any infections. HIV antibodies were determined by enzyme-linked immunosorbent assay (ELISA) using Genscreen HIV 1/2 Kit. Results: The results were found to be 99% sensitive and 100% specific for saliva samples, while it was 100% sensitive and specific for serum samples. Conclusion: Saliva can be used as alternative to blood for detection of HIV antibodies as saliva collection is painless, non-invasive, inexpensive, simple, and rapid. Salivary antibody testing may provide better access to epidemic outbreaks, children, large populations, hard-to-reach risk groups and may thus play a major role in the surveillance and control of highly infectious diseases.

Purpose: To evaluate the correlation between CD4+ cells count with orofacial and systemic manifestations in newly diagnosed HIV seropositive patients and comparison of results with the previous studies. Materials and Methods: Hundred (100; 57 males and 43 females) newly diagnosed HIV seropositive patients, before starting antiretroviral therapy (ART) were included in the study. These patients were clustered according to CD4+ cells count into three groups: 0–200 cells/mm 3 , 201–499 cells/mm 3 , and more than 500 cells/mm 3 . Orofacial and systemic manifestations of these patients were recorded and correlated with CD4 cells count values. Results: There was no significant correlation found between CD4+ cells count values of males and females using independent t -test. Chi-square test showed significant correlation between the systemic manifestations and CD4+ cells count categories. Tuberculosis was found to be the most common systemic manifestation in both the genders. In addition, a significant correlation was between the CD4+ cells count and orofacial manifestations, where oral candidiasis was found to be the most common manifestation in both the genders. Conclusion: The prevalence of systemic and orofacial manifestations increases with decrease in the CD4+ cells count of HIV seropositive patients. Hence, it can be used as diagnostic and prognostic marker for immune suppression in HIV positive patients.

Aim: This study was intended to evaluate the knowledge and apprehension of dental health professionals pertaining to COVID-19. Materials and Methods: In this cross-sectional survey, a self-administered questionnaire survey was used to validate the dental health professional's knowledge and apprehension pertaining to COVID-19. In this regard, a preliminary study with a convenience sample of 124 dentists working in various clinics in southern India was conducted so as to evaluate the knowledge and apprehension of dentists related to COVID-19 in India. This study, while limited in sample size, benefits the general practitioners as target readers to assess the awareness pertaining to COVID-19. Results: The results of this study reveal that there exists a good knowledge among dental health professionals pertaining to the COVID-19 virus and its oral manifestations in addition to the precautions to be taken for the prevention of COVID-19 in a clinical setup. However, there exists an apprehension as well as lack of awareness pertaining to the laboratory test to be carried out in a patient suspected with COVID-19 infections as well as the role of a mouthwash and the management of contaminated air in the dental clinic. Conclusion: The results elicited that there is a dearth of knowledge and relatively a fair apprehension among dental health professionals pertaining to COVID-19.

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Introduction: At the time when the world was unprepared for the corona pandemic, the health-care workers faced the challenge with great effort. Recently, the OMICRON has been burdening the medical fraternity. Hence, in our study, we aimed to evaluate the “knowledge, attitude, and practices” related to OMICRON among the medical health-care staff. Materials and Methods: We piloted an online cross-sectional questionnaire study using Google Forms among 1000 medical staff working at various levels of public and private sections. The questions were formulated to test for the practices, attitude, and knowledge of the new variant OMICRON. The data collected were compared using the Chi-square test, deliberating P < 0.05 as significant. Results: We observed that majority were male participants, with significant number at the ages of 20–40 years. There was lower knowledge, although good practice and positive attitude were noted among the medical health staff. Conclusion: The medical health-care personnel possessed less knowledge regarding the new variant OMICRON, although positive practices and attitudes were noted. Hence, the governments should take necessary steps to implement the training about the new variant.