Absrracr. 35 patients with Hodgkin's disease, 13 patients with other lymphomas and 26 control subjects have been typed for 8 HL-A antigens.The frequency of HL-A8 and HL-A7 was higher among the patients with Hodgkin's disease and other lymphomas than among control subjects. In contrast to findings reported by others we did not find any difference in HL-A5 frequency between patients with Hodgkin's disease and control subjects.

In 39 cholecystectomized patients and 62 patients without previous cholecystectomy the effect of i.m. injection of morphine on the serum concentrations of bilirubin, alkaline phosphatase, GOT, GPT, LDH and amylase has been studied. Most of the cholecystectomized patients in whom the injection of morphine provoked a reaction of abdominal pain showed increased serum activity of both GOT and GPT 8 hours after the injection of morphine. The results suggest that this "morphineenzyme-pain provocation" may be helpful in differentiating dyskinesia of the sphincter Oddi from other postcholecystectomy abdominal complaints.Acta vied. scattd. 194

Abstract. A group of 38 patients with lymphomas (29 with Hodkin's disease and 9 with other lymphomas) and a control group of 27 healthy individuals were vaccinated with an influenza vaccine, containing influenza A Hong Kong virus. Eight patients (6 with Hodgkin's disease and 2 with other lymphomas) did not respond with a fourfold raise in titre or greater as measured by haernagglutination inhibition assay. In the healthy control group, everyone showed an adequate antibody response. In the patients, incapacity of antibody formation was not associated with cytostatic therapy, treatment with prednisone or the combination of the two, but a correlation was found with radiation therapy during the ‘immunization period’. HL‐A typing and determination of serum immunoglobulin levels were performed both in the patients and in the healthy controls. A significant difference in HL‐A12 frequency was found between patients with adequate antibody response to influenza vaccination (HL‐A12 frequency 13%) and those without demonstrable antibody formation (HL‐A12 frequency 62%). No significant differences in serum immunoglobulin levels were noted between the patients and the control persons.

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