Objectives. To enhance student curricular satisfaction, position students for multiple career options, and counter the national deficit in pharmacy faculty members by creating a research elective for students enrolled in a first-professional degree PharmD program. Design. The research track consists of 12 credit hours of didactic, seminar, and research courses. This concentration option entails graduate-level coursework and 2 consecutive semesters of attending a graduate seminar course and conducting independent but faculty-mentored basic science or pharmacy administration research. Assessment. Current PharmD students and recent PharmD graduates provided feedback on their experience via e-mail, telephone or in person. Conclusion. In its second year of existence, the Duquesne University pharmaceutical sciences research track option has been positively received by PharmD students, has successfully directed PharmD students toward research-based careers, and may serve as a template for similar concentrations at other colleges and schools of pharmacy.
A monoclonal antibody, EIV-E12, was produced against ellipsoid-associated cells. In postnatal chicks, the antigen defined by EIV-E12 associated with about 90% of bursal cells and accumulated in B cell-rich areas of lymphoid organs. The antigen was expressed by many splenic cells on day 9 of embryogenesis and about 1 day later in the bursal anlage, where the cells positive for the antigen localized in close proximity to the plical epithelium. In the bursa, these early EIV-E12 cells appeared before Bu-1-positive cells and may represent a dendritic cell precursor. B cells within the developing bud acquired the EIV-E12 antigen. Immunoprecipitation studies revealed a molecular weight of 233 (nonreduced) and 205 (reduced) for the EIV-E12 antigen. These values were markedly different from the molecular weight of the antigen identified by Bu-1 but similar to that of a CB10 antigen. The CB10 and EIV-E12 MAbs exhibited some differences in cellular staining. Taken together these data suggest that EIV-E12 MAb recognizes a unique cellular population during embryogenesis.
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