Purpose: The Prevalhep study seeks to determine the prevalence of factors associated with hepatitis C virus (HCV) and B (HBV) in Spanish prisoners Methods: Observational, cross-sectional study which randomly selected 18 Spanish prisons to participate, and with 21 prisoners/CentreResults: There were 378 prisoners selected, 370 of whom had serological HCV and 342 had VHB data. The HCV population were predominantly male (91.6%), of middle age (66.7% contact status with HBV (HBcAb+ and/or HBsAg+), while 37.5% were susceptible to HB.
Conclusions:The prevalence of HBV and HCV has decreased in the Spanish prison population, probably as a result of decrease in IDU transmission, and an increase in immigrant prisoner population that does not have this risk behaviour.[Word count = 198]
Randomized trials of thienopyridines in patients with vascular disease demonstrate that thienopyridines are effective in reducing vascular events when compared with placebo/control or aspirin, as well as when used in combination with aspirin in patients undergoing intracoronary stent implantation. The CURE trial is a large international study to determine if acute and long-term treatment with the combination of clopidogrel and aspirin is superior to aspirin alone in patients with acute coronary syndrome.
Objective: To determine the prevalence and associated factors of HIV infection amongst inmates in Spain. Material and Methods: Observational and transversal study (June 2008). For 62,000 inmates an "n" of 364 was determined (5% variability, error correction α 5% and 10% missing). 18 prisons were randomly selected and 21 inmates/prison. Frequency measurement: prevalence. Magnitude of the association: odds ratio of prevalence (ORP) with 95%. Statistical significance p<0.05. results: 371 prisoners were studied (91.6% male, 66.9% ≤ 40 years, 60.6% Spanish, 23.5% IDU and 71.2% incarcerated <5 years). HIV prevalence was 10.8% (CI: 7.5 to 14). 85% were co-infected with HCV, 12.5% with HBV and HCV and 63.2% with M. tuberculosis. This represents a proportion to the prison population of 9.2%, 1.3% and 6.7% respectively. HIV infection was associated with: a) > 40 years (p <0.01), b) imprisoned> 5 years (p <0.001), c) non-Arab (p <0.01), d) Spanish nationality (p <0.001), e) IDUs (p <0.001), f) co-infected with HCV (p <0.001), and g) co-infected with HBV (p <0.001]. Multivariate analysis confirmed the association: a) ≥ 40 years [
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.