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Neither strategy was effective in improving the appropriateness of OTC management of vulvovaginal candidiasis by community pharmacy staff. Further research is needed to identify barriers to guideline implementation and evidence-based practice in this setting.

Objective-To evaluate guidelines for general practice management and referral of infertile couples. Guidelines were implemented with a disease specific reminder at the time of consultation (the guidelines were embedded within a structured infertility management sheet for each couple).Design-Pragmatic randomised controlled trial. Participating practices were randomised to a group that received the guidelines and a control group.Setting-82 general practices in Grampian region. Subjects-100 couples referred by general practitioners receiving the guideline and 100 couples referred by control general practitioners.Main outcome measure-Whether the general practitioner had taken a full sexual history and examined and investigated both partners appropriately.Results-Characteristics of patients referred by study and control general practitioners did not differ significantly at baseline. Compliance with the guidelines increased for all targeted activities. General practitioners in the study group were more likely to take a sexual history (for example, couples' use of fertile period, 85% v 69'/6, p <0.01); examine both partners (female partner, 68% v 52%, p < 0-05; male partner 390/ v 13%, p <0.01); and investigate both partners (day 21 progesterone, 72% v 41%, p< 0 l001; semen analysis, 51% v 41%, p>005). Improvements were greater when general practitioners used the disease specific reminder.Conclusion-Receiving guidelines led to improvements in the process of care of infertile couples within general practice. This effect was enhanced when the guidelines were embedded in a structured infertility management sheet for each couple.

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