The application of the IMRT techniques in radiotherapy patients with early-stage breast cancer allows to obtain more homogenous dose distribution in target volume, while permitting to reduce the dose to critical organs.

1. ¹⁸F-FDG PET/CT is useful in the diagnosis of radioiodine-negative DTC in patients with high levels of stimulated Tg. 2. The sensitivity of ¹⁸F-FDG PET/CT increases with stimulated Tg levels. At stimulated Tg > 28.5 ng/ml, the sensitivity of the study reaches 100%.

Compared with 3D-CRT, the application of IMRT improves the dose distribution within the concave target volumes and reduces dose to the OAR structures without compromising target coverage.

No abstract

The aim of this study is to investigate secondary mixed radiation field around linac, as the first part of an overall assessment of out-of-field contribution of neutron dose for new advanced radiation dose delivery techniques. All measurements were performed around Varian Clinic 2300 C/D accelerator at Maria Sklodowska-Curie Memorial, Cancer Center and Institute of Oncology, Krakow Branch. Recombination chambers REM-2 and GW2 were used for recombination index of radiation quality Q4 determination (as an estimate of quality factor Q), measurement of total tissue dose Dt and calculation of gamma and neutron components to Dt. Estimation of Dt and Q4 allowed for the ambient dose equivalent H*(10) per monitor unit (MU) calculations. Measurements around linac were performed on the height of the middle of the linac's head (three positions) and on the height of the linac's isocentre (five positions). Estimation of secondary radiation level was carried out for seven different configurations of upper and lower jaws position and multileaf collimator set open or closed in each position. Study includes the use of two photon beam modes: 6 and 18 MV. Spatial distribution of ambient dose equivalent H*(10) per MU on the height of the linac's head and on the standard couch height for patients during the routine treatment, as well as relative contribution of gamma and neutron secondary radiation inside treatment room were evaluated.