SelectiveReduction of Carbonyl Compounds with Al-Alkoxydiisobutylalanes.-The title alanes, e.g. iBu 2 Al-O-Et, only reduce aldehydes and ketones such as (I), (III), (V), and (VII), whereas esters, nitriles and acid chlorides are not attacked. Highly chemoselective discrimination between structurally different ketones, c.f. (IX)/(X), between aldehydes and ketones, c.f. (Ia)/(Id), and between aldehydes, c.f. (Ib)/(XIII), is possible. Stereoselective reductions are achieved using iBu 2 Al-O-iPr. -(CHA, J. S.; KWON, O. O.; KIM, J. M.; CHUN, J. H.; LEE, Y. S.; LEE, H. S.; CHO, S. D.; Bull.

Reduction of Disulfides to Thiols with Lithium Tris(dialkylamino) aluminum Hydrides.-Lithium tris(dialkylamino)aluminum hydrides readily reduce both aliphatic and aromatic disulfides in essentially quantitative yield to the corresponding thiols (II) (4 examples) without any evolution of hydrogen. -(CHA, J. S.; KIM, J. M.; JEOUNG, M. K.; LEE, K. D.; Bull.

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1995 reduction, hydrogenation reduction, hydrogenation O 0220 28 -063 Transformation of Carboxylic Esters to Aldehydes with Sodium Tris( diethylamino)aluminum Hydride. -The new reducing reagent, sodium tris(diethylamino)aluminum hydride reduces esters to aldehydes more selectively and under milder conditions than lithium tris(diethylamino)aluminum hydride. -(CHA, J. S.; KIM, J. M.; JEOUNG, M. K.; KWON, O. O.; KIM, E. J.; Org. Prep. Proced. Int. 27 (1995) 1, 95-98; Dep. Chem., Yeungnam Univ., Kyongsan 712-749, S. Korea; EN)

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.