Cerebral malaria is a significant cause of childhood morbidity in our region. The challenges of effective management include time and quality of treatment. The study appraised the health care seeking behavior of caregivers of sick children who developed cerebral malaria, in Zaria, northwestern Nigeria. Caregivers indentified were parents 29 (87.9%) and grandparents 4 (12.1%). Most of them were in the upper social classes. Health care options utilized before presentation at our facility were formal health facility 24 (72.7%), patent medicine seller 12 (36.4%), home treatment 10 (30.3%), and herbal concoction 6 (18.2%) with majority 24 (72.7%) using more than one option. Antimalarial therapy was instituted in 25 (75.6%) of the cases. Mortality was significantly associated with the use of herbal concoction, treatment at a formal health facility and patent medicine seller, multiple convulsions, age less than 5 years, and noninstitution of antimalarial therapy before presentation. The study showed use of inappropriate health care options by caregivers and highlighted the need to pursue an awareness drive among caregivers on the use of health care options.

Nutrition is a major factor that can have long-term effects on the brain's structural and functional capacity. The interplay between nutrition and child development cannot be overemphasised, especially in developing countries. Objectives: The study aimed to assess the nutritional status of under-fives and determine the relationship between the nutritional status and their developmental quotient. Methodology: A cross-sectional study was undertaken involving 415 under-fives aged 6-59 months in selected pre-schools and immunisation centres. Developmental assessment was done using the Schedule of Growing Skills II. The nutritional status was assessed using the WHO growth charts for weight-forage , weight-for-height and height-forage. Chi-square and odds ratio with 95% confidence interval were used to determine the association between nutritional status and selected developmental domains. Results: The mean age was 32.6 ± 15.9 months. The male to female ratio was 1.2:1. The overall prevalence of developmental delay was 35.4%, with manipulative domain accounting for the highest delay (25.8%). The prevalence of stunting, wasting and underweight was 9.1, 3.8 and 3.8% while 2.2% were overweight. Weight-forage had a significant association with the hearing and language domain (OR 3.25, 95% CI 1.09-9.72, p = 0.036,) and interactive social domain (OR 5.0, 95% CI 2.0-13.0, p = 0.001). Conclusion: The nutritional status of a child has an effect on certain developmental domains of that child. Interventions to improve the nutritional status of under-fives will go a long way to facilitating the development of this group of children.

Over one-third of patients undergoing surgical correction of congenital malformations have co-existing CHD. Echocardiography is important for pre-surgical evaluation. No association between type of CHD and specific non-cardiac congenital malformations was found.

Identifying AKI associated with DEG is difficult. Detailed drug history, increasing metabolic acidosis, and multiorgan deterioration despite peritoneal dialysis should arouse suspicion. Simple diagnostic tests need to be developed and facilities for hemodialysis of infants and financial support provided. Recurrences can be prevented by creating awareness, improving manufacturing practices, field-testing of drugs, and international monitoring of pharmaceuticals imported for manufacture.