1993. Biochemical indicators of oxidative stress in fish from polluted littoral areas. Can. ). Fish, Aquat. Sci. 50: 2568-2573.Several biochemical parameters have been analyzed in the h e r s of fish from south Atlantic Spanish littoral areas exhibiting different pollution levels. Mugil sp. (grey mullet) from the Huelva Estuary contained higher concentrations of metals, such as Fe and Cu, than those from a reference area (Ciidiz Bay). Similarly, sediments from Huelva showed high concentrations of polyaromatic hydrocarbons, polychlorinated biphenyls, and pesticides. The contaminated animals were subjected to oxidative stress, as indicated by their oxidized glutathione redox status, but shacved low malondialdehyde and Bipohydroperoxide levels. A battery of antioxidant enzymes increased simultaneously in contaminated fishes, including glutathione peroxidase, superoxide disrnutase, catalase, glucose-6-P dehydrogenase, and glutathione reductase. These data suggest that contaminated fish were \veil protected from oxidative stress. Highly significant increases were also observed in cytochrome P-450-associated ethoxyresorufin-0-deethylase activity, and soluble and membrane-bound glutathione-Stransferase, in response to the high levels of organic xensbiotics. We propose that antioxidant enzymes and glutathione-S-transferase might be useful tools for the biomonitoring of environmental pollution.On a 6tudi6 plusieurs pararn&tres dans les foies des psissons provenant des zones avec diff6rents niveaux de pollution au long du littoral Sud-Atlantique espagnol. Ees individus de Mugilsp. provenant de B'estuaire de Huelva contenaient des concentrations en Fe, Cu plus grandes que ceux qui provenaient d'une zone de reference (C5diz). En plus, les sediments de Huelva contenaient concentrations plus grandes de hidrocarbsns polyaromatiques,
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.